The Nevada National Board Professional Learning Institute | Schmitt | Activity

Schmitt posted an update: Individuals with substance use disorders (SUDs), including […]

Sun, 09 Feb 2025 09:50:46 -0800

Individuals with substance use disorders (SUDs), including those in long-term recovery, and their loved ones are facing rapid changes to treatment and support services due to COVID-19. To assess these changes, the Addiction Policy Forum fielded a survey to their associated patient and family networks between April 27 and May 13, 2020. Individuals…[Read more]

Schmitt posted an update: Protein-bound uremic toxins (PBUTs) and liver […]

Mon, 03 Feb 2025 09:38:15 -0800

Protein-bound uremic toxins (PBUTs) and liver failure-related cholestatic solutes are associated with adverse outcomes in patients with chronic kidney disease (CKD) and liver failure, respectively, and are not easily removed by traditional dialysis therapies. We constructed linoleic acid-modified liposomes (LA-liposomes) as indirect adsorbent in…[Read more]

Schmitt posted an update: Low concentrations of biomarkers as well as the complexity […]

Thu, 30 Jan 2025 09:35:28 -0800

Low concentrations of biomarkers as well as the complexity of biological samples make the clinical diagnoses of several diseases a challenging task. Sample preparation protocols remain a fundamental piece in the puzzle of analytical processes, and smart sorbents including molecularly imprinted polymers (MIPs) have been successfully used in this…[Read more]

Schmitt posted an update: Resveratrol modulates the transcription factor NF-κB, […]

Thu, 30 Jan 2025 06:50:50 -0800

Resveratrol modulates the transcription factor NF-κB, cytochrome P450 isoenzyme CYP1A1, expression and activity of cyclooxygenase (COX) enzymes, Fas/Fas ligand mediated apoptosis, p53, mTOR and cyclins and various phospho-diesterases resulting in an increase in cytosolic cAMP levels. Cyclic AMP, in turn, activates Epac1/CaMKKβ/AMPK/SIRT1/PGC-1α pa…[Read more]