The Nevada National Board Professional Learning Institute | Carver | Activity http://www.nationalboardinstitute.com/members/hooksquare89/activity/ Activity feed for Carver. Fri, 23 May 2025 17:06:54 -0700 https://buddypress.org/?v=9.1.1 en-US 30 hourly 2 8936e159eaee0117b8f6c082efae8655 Carver posted an update: We found that topography and morphological features of the […] http://www.nationalboardinstitute.com/activity/p/41946/ Sat, 08 Feb 2025 11:38:28 -0800 We found that topography and morphological features of the substrate are the properties that mainly drives astrocytes adhesion and survival, over the long term, while they do not alter the cell function. Specifically, aligned PCL fibres induced in astrocytes a dramatic actin-cytoskeletal rearrangement as well as focal adhesion point number and…[Read more]

]]> 0 20def8755ca7372f8788ff56313b49b8 Carver posted an update: Long non-coding RNAs such as C058791.1, TTTY15 and TPTEP1 […] http://www.nationalboardinstitute.com/activity/p/41179/ Fri, 07 Feb 2025 11:41:51 -0800 Long non-coding RNAs such as C058791.1, TTTY15 and TPTEP1 were predicted to be efficient in regulating the disease mechanisms. Drugs-F-1566-0341, Digoxin, Proscillaridin and Linifanib that reverse the gene expression signatures were predicted from drug perturbations analysis. The binding efficiency and interaction of proscillaridin and digoxin as…[Read more]

]]> 0 e554ecd63ea6b01214dab5d6ab11781c Carver posted an update: Metabolic reprogramming is a common hallmark of cancer, but […] http://www.nationalboardinstitute.com/activity/p/39284/ Wed, 05 Feb 2025 12:20:04 -0800 Metabolic reprogramming is a common hallmark of cancer, but a large variability in tumor bioenergetics exists between patients. Using high-resolution respirometry on fresh biopsies of human lung adenocarcinoma, we identified 2 subgroups reflected in the histologically normal, paired, cancer-adjacent tissue high (OX+) mitochondrial respiration and…[Read more]

]]> 0 fdaa9ca6d5c0fdccf5a709996e975820 Carver posted an update: PIs related to drug-drug interactions (10%) mainly had a […] http://www.nationalboardinstitute.com/activity/p/37618/ Mon, 03 Feb 2025 11:35:53 -0800 PIs related to drug-drug interactions (10%) mainly had a moderate and major clinical impact (82.3%, p<0.0001).

Clinical pharmacists play a key role for detecting drug-related problems mostly leading to a change in therapeutic management among LT outpatients. Our study provides a new insight to analyse the clinical impact of PIs in order to…[Read more]

]]> 0 cbd01f5f9f85d9d53a799e00156bfb7b Carver posted an update: The analysis of plasma circulating tumour nucleic acids […] http://www.nationalboardinstitute.com/activity/p/35954/ Sat, 01 Feb 2025 11:59:04 -0800 The analysis of plasma circulating tumour nucleic acids provides a non-invasive approach to assess disease burden and the genetic evolution of tumours in response to therapy. BRAF splicing variants are known to confer melanoma resistance to BRAF inhibitors. We developed a test to screen cell-free RNA (cfRNA) for the presence of BRAF splicing…[Read more]

]]> 0 b24fcf2c78b81e45624af89fdf1559cb Carver posted an update: Ring conformations of 3,4-dihydro-2H-pyran (34DHP) have […] http://www.nationalboardinstitute.com/activity/p/34752/ Fri, 31 Jan 2025 11:11:20 -0800 Ring conformations of 3,4-dihydro-2H-pyran (34DHP) have attracted considerable interest owing to their structural similarity to cyclohexene, an important molecule in stereochemistry. In this study, we investigated the conformational interconversion of 34DHP in both the neutral (S0) and the cationic (D0) ground states. High-resolution vacuum…[Read more]

]]> 0 e7b9e6d1f14cbdfc424562d36a6e2beb Carver posted an update: Analogs of dirchromone were prepared to shed light on the […] http://www.nationalboardinstitute.com/activity/p/30756/ Tue, 28 Jan 2025 15:40:46 -0800 Analogs of dirchromone were prepared to shed light on the pivotal role of its peculiar vinylsulfoxide side chain towards its cytotoxic and antimicrobial properties, especially dependant upon the presence and oxidation state of sulfur. The reaction of dirchromone with cysteamine revealed a surprising Michael acceptor behavior with elimination of…[Read more]

]]> 0 e0cc3687abc73862df5537becb3bb701 Carver became a registered member http://www.nationalboardinstitute.com/activity/p/30708/ Tue, 28 Jan 2025 15:37:32 -0800 0