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	<title>The Nevada National Board Professional Learning Institute | Charles | Activity</title>
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				<title>Charles posted an update: Metastatic melanoma remains a challenging disease. [&#133;]</title>
				<link>http://www.nationalboardinstitute.com/activity/p/31620/</link>
				<pubDate>Tue, 28 Jan 2025 17:10:43 -0800</pubDate>

									<content:encoded><![CDATA[<p>Metastatic melanoma remains a challenging disease. Understanding the molecular mechanisms how melanoma becomes metastatic is therefore of interest. Herein we show that downregulation of the AP-1 transcription factor member Fra-2 in melanoma cells is associated with an aggressive melanoma phenotype in vitro and in vivo. In vitro, Fra-2 knockdown in&hellip;<span class="activity-read-more" id="activity-read-more-31620"><a href="http://www.nationalboardinstitute.com/activity/p/31620/" rel="nofollow ugc">[Read more]</a></span></p>
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				<title>Charles became a registered member</title>
				<link>http://www.nationalboardinstitute.com/activity/p/31575/</link>
				<pubDate>Tue, 28 Jan 2025 17:05:44 -0800</pubDate>

				
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