The Nevada National Board Professional Learning Institute | Tobin | Activity http://www.nationalboardinstitute.com/members/randomcheek7/activity/ Activity feed for Tobin. Fri, 23 May 2025 17:06:54 -0700 https://buddypress.org/?v=9.1.1 en-US 30 hourly 2 a03a4a57e77a0b05d30f5dbc87db2a46 Tobin posted an update: Discussion  It is important to exclude significant o […] http://www.nationalboardinstitute.com/activity/p/39533/ Thu, 06 Feb 2025 08:49:11 -0800 Discussion  It is important to exclude significant obstruction when a large AMVT is seen to be prolapsing into the LVOT. Three-dimensional echocardiography is the tool of choice for anatomical classification and to assess for concomitant congenital cardiac abnormalities. © The Author(s) 2020. Published by Oxford University Press on behalf of th…[Read more]

]]> 0 d3cddb5709e7e45e218c29fbaf88f2ca Tobin posted an update: In a recent publication, we demonstrated that conditional […] http://www.nationalboardinstitute.com/activity/p/37987/ Tue, 04 Feb 2025 08:53:40 -0800 In a recent publication, we demonstrated that conditional deletion of the gene encoding thymine DNA glycosylase (TDG) leads to a late onset of hepatocellular carcinoma (HCC). TDG loss causes disruption in active DNA demethylation in the liver and dysregulation of the farnesoid X receptor and small heterodimer partner (FXR-SHP) regulatory cascade.…[Read more]

]]> 0 3b51d15ba1725a32b3f481512d4ee0aa Tobin posted an update: Quantitative analysis of vacuolar areas in the spinal cord […] http://www.nationalboardinstitute.com/activity/p/37107/ Mon, 03 Feb 2025 09:00:32 -0800 Quantitative analysis of vacuolar areas in the spinal cord showed a strong correlation with hind limb crossing sign scores. In conclusion, evaluation of plasma -SHp levels allowed us to detect individuals at risk for health damage and could protect the sensitive population against MeHg toxicity.The nitrate content of the most consumed green leafy…[Read more]

]]> 0 e9e3c4a784a4e37fac23035fafe3c128 Tobin posted an update: To analyse the population pharmacokinetics (PK) of […] http://www.nationalboardinstitute.com/activity/p/35285/ Sat, 01 Feb 2025 08:54:13 -0800 To analyse the population pharmacokinetics (PK) of peficitinib in patients with rheumatoid arthritis (RA) and assess the potential PK covariates to identify the requirement for dose adjustment in RA patients.

The analysis incorporated 2464 observations from 98 healthy volunteers and 4919 observations from 989 RA patients. A population PK…[Read more]

]]> 0 78b82d80eabde129057857be6163a5b5 Tobin posted an update: Forty (13%) out of 300 patients had at least one […] http://www.nationalboardinstitute.com/activity/p/33289/ Thu, 30 Jan 2025 08:47:56 -0800 Forty (13%) out of 300 patients had at least one complication in the OR, as defined by persistent coughing, desaturation SpO

 < 90% for longer than 10s, laryngospasm, stridor, bronchospasm and reintubation. When comparing the complication group to the no complication group, the patients in the complication group had significantly higher BMI…[Read more]

]]> 0 3ffdb2fdc14462c0218fb8e8cbd66560 Tobin posted an update: Soft robots show excellent body compliance, adaptability, […] http://www.nationalboardinstitute.com/activity/p/33068/ Thu, 30 Jan 2025 05:00:40 -0800 Soft robots show excellent body compliance, adaptability, and mobility when coping with unstructured environments and human-robot interactions. However, the moving speed for soft locomotion robots is far from that of their rigid partners. Rolling locomotion can provide a promising solution for developing high-speed robots. Based on different…[Read more]

]]> 0 68883a27aa2af6f19d80ff622c597614 Tobin posted an update: Animals treated with losartan showed a reduction in […] http://www.nationalboardinstitute.com/activity/p/30759/ Tue, 28 Jan 2025 15:41:00 -0800 Animals treated with losartan showed a reduction in cathepsin activity and restored ERK1/2 activation. While both losartan and propranolol improved heart function, no mechanistic evidence was found for propranolol so far. Our results suggest that losartan or propranolol could be used to ameliorate the cardiac disease in MPS I and could be…[Read more]

]]> 0 52d5bc18b8d4fd0d790db874f108285f Tobin became a registered member http://www.nationalboardinstitute.com/activity/p/30720/ Tue, 28 Jan 2025 15:38:10 -0800 0