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Patients with stage I anal squamous cell carcinoma (SCC) have been underrepresented in landmark trials showing superiority of chemoradiotherapy over radiotherapy for definitive treatment. This review aims to elucidate whether definitive treatment with radiotherapy versus chemoradiotherapy is associated with differences in survival and…[Read more]

Spontaneous coronary artery dissection (SCAD) is a rare cause of myocardial infarction, presenting mostly in healthy, young women. The pathogenesis is still poorly understood. A 45-year-old woman presented with an ST-elevation myocardial infarction, caused by SCAD of the mid left anterior descending coronary artery. In the six years prior to this…[Read more]

6-0.0 seconds before triggering (REST r = 0.77, P = .009, RACE r = 0.88, P = .001) and less aiming point movement 0.2-0.0 seconds before triggering (REST r = 0.82, P = .003, RACE r = 0.72, P = .012) in TIMING. Postural balance was related to shooting performance at REST in both groups and in RACE in TIMING. Biathletes using the hold strategy…[Read more]

MoS2 intrinsically show Pt-like hydrogen evolution reaction (HER) performance. Pristine MoS2 displayed low HER activity, which was caused by low quantities of catalytic sites and unsatisfactory conductivity. Then, phase engineering and S vacancy were developed as effective strategies to elevate the intrinsic HER performance. Heterojunctions and…[Read more]

THIM is a new wearable device worn on the finger that can passively monitor sleep and wakefulness overnight using actigraphy. This article showcases the development of the THIM sleep tracking algorithm (Study 1) and the testing of its accuracy against polysomnography (PSG) with an independent sample of good and poor sleepers (Study 2). The…[Read more]

Results show that the model is computationally efficient, and the predicted jumping motion matches the experimental data trend. The simulation model can predict vertical jumping motion and can test the effect of different loading conditions with weighted vests and arm-swing strategy on the ground reaction forces. This work is novel in the sense…[Read more]

Static pressure tubes are widely used to measure the static pressure in turbulent flows. Existing work focuses on the alteration of the static pressure tubes to the flow field. This paper investigates the effects of the geometric properties of a static pressure tube on the frequency response. A theoretical formulation is developed to describe the…[Read more]

The modalities by which chronic pain can be successfully managed include genicular nerve radioablation therapy (GN-RFA), neuromuscular electrical stimulation (NMES), transcutaneous electrical nerve stimulation (TENS), and peripheral subcutaneous field stimulation (PSFS). Meta-analyses and case reports have demonstrated the effectiveness of these…[Read more]

A new fluorescence probe L, which featured with a large Stokes shift (216 nm), was designed for sensitive detection of cysteine (Cys) and a potential sensing mechanism derived from excited state intramolecular proton transfer (ESIPT) was proposed. More importantly, probe L exhibits higher selective to Cys than other amino acid due to its s…[Read more]

Snake bite continues to be a significant cause of acute kidney injury (AKI) in India. There is paucity of data regarding long-term outcomes of such patients. In this study, we aim to assess the prognosis and long-term renal outcomes of such patients.

We analysed the hospital records of snake envenomation-induced AKI from January 2015 to…[Read more]

Careful consideration of radiotherapy can determine the success of reconstructive therapy. There is a broad spectrum of radiotherapy modalities, both benign and malignant. Delivery mechanisms differ in the physical design, setup, radiation source, administrable dosage, and mode of delivery. This range of options allows radiation oncologists to…[Read more]

learning content through practice constitutes the key element for transfer into long-term memory.

This study demonstrated significant learning success for both groups in their own self-assessment as well as in the results of the practical exercises. Subsequently, the superiority of the PDCA cycle could be shown for almost all criteria for…[Read more]

Coronary artery disease (CAD) risk increases in proportion to the magnitude and duration of exposure to plasma low-density lipoprotein cholesterol (LDL-C), doubling every additional decade of exposure. Early primary prevention is three times more effective than initiated later. Several clinical trials show plasma LDL-C of 15-40 mg/dL is more…[Read more]

By training the proposed network in an end-to-end manner, all learnable modules can be automatically explored to well characterize the representations of both JPEG artifacts and image content. Experiments on synthetic and real-world datasets show that our method is able to generate competitive or even better deblocking results, compared with…[Read more]

As cases of COVID-19 climb worldwide, academic medical centers (AMCs) are scrambling to balance the increasing demand for medical services while maintaining safe learning environments. The scale and nature of the current pandemic, limitations on key resources, risks of transmission, and the impact on trainee wellbeing pose additional challenges to…[Read more]

UV-H2O2 is the most widely used oxidizing system with established effectiveness and a high level of technical development for practical application. However, little attention was paid on the effect of suspended particles in natural water on organic contaminants removal via UV-H2O2 technique. In this study, this effect of suspended particles to…[Read more]

Limitations of local imaging resources and capacity should be identified and inform plans for the utilization of diagnostic radiology in the MCI setting. Simulation can help identify areas for improvement and familiarize staff with their roles. Further development of reliable MCI alert technology and patient identification strategies are needed as…[Read more]

ins cross talk to establish native CRISPR anti-virus immunity in a Sulfolobales cell.Four new purified polysaccharides (PAP) were isolated and purified from the Enteromorpha prolifera by alkali extraction, and further characterization was investigated. Their average molecular weights of PAP-1, PAP-2, PAP-3, and PAP-4 were estimated as 3.44 × 104,…[Read more]

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and quickly spread around the world, forcing global health authorities to develop protocols for its diagnosis. Here we report dimer formation in the N2 primers-probe set (CDC 2019-nCoV Real-Time RT-PCR) used in the diagnostic routine, and propose alternatives to…[Read more]

Together these results demonstrate that coral genets from isolated sanctuaries such as FGBNMS can withstand pathogen challenges and potentially aid restoration efforts in degraded reefs. Furthermore, gene expression signatures associated with resistance and long-term growth help inform strategic assessment of coral health parameters.We report the…[Read more]