Activity

In all cases, PI values tripled at 5 min after the block execution and increased linearly, reaching at 10 min an average PI value 3.8 times higher for the interscalene group, 4 times for the spinal group, and 8 for the sciatic group.

A tripled PI within 5 min from performing regional anesthesia showed to be a reliable indicator of nerve block success, but a bigger trial involving more patients and different anesthetic concentrations may be necessary to confirm this assumption.

A tripled PI within 5 min from performing regional anesthesia showed to be a reliable indicator of nerve block success, but a bigger trial involving more patients and different anesthetic concentrations may be necessary to confirm this assumption.

The objective was to study the extent of anaesthetic intervention and its association with systemic comorbidities. The secondary objectives were to estimate the prevalence of systemic comorbidities in age-related cataracts.

To determine the prevalence of systemic comorbidities in cataract surgery patients and association with anaesthesiologists’ intervention.

Prospective observational study.

The study was done inatertiary care hospital over a period of 3 months. Adult and consenting patients were included and those having sensitivity or toxic reaction to local anaesthetics, uncooperative, and paediatric patients were excluded.

The sample size (717) was calculated according to the formula for the finite population. The total number of patients suffering from comorbidities, adverse events during surgery, and events attended by an anesthesiologist with percentages were calculated.

Of the 717 patients studied, comorbidities were associated with 385 (53.69%) patients; among which hypertension was most frequent and found in 174 (20.30%). As much as 113 (15.72%) patients had adverse events during surgery and required intervention by the attending anaesthesiologist in which 26 (15.72%) patients required drug administration for stabilization of condition of the patient.

From this study, we conclude that there is a correlation between prevalent comorbidities and active intervention by the attending anaesthesiologist in patients undergoing cataract surgery.

From this study, we conclude that there is a correlation between prevalent comorbidities and active intervention by the attending anaesthesiologist in patients undergoing cataract surgery.

Nowadays, cardiovascular diseases such as coronary heart disease are one of the most important causes of human mortality worldwide. Coronary artery bypass graft (CABG) surgery is a standard therapy approach for those suffering from coronary artery disease. Tranexamic acid (TXA), an antifibrinolytic drug, which, in turn, inhibits fibrinolysis, leading to the prevention of bleeding, thus, the present study aimed to evaluate the effect of topical TXA on bleeding reduction after coronary artery CABG.

In this study 62 patients were randomly divided into two groups of TXA and control. After surgery and removal from the cardiopulmonary pump, TXA (2 g) was injected locally into the mediastinum by the surgeon. In the second group (control) the same amount of normal saline (100 cc) was given. Data were analyzed by SPSS 19 software via the

-test and Fisher’s test.

A significant difference was found between the 2 groups in terms of postoperative hemorrhage, packed cell volume, platelet transfusion, duration of surgery, and received FFP (

= 0.0001;

= 0.01;

= 0.0001;

= 0.0001;

= 0.0001), where were found to be lower in the TXA group than in the placebo group. There was no significant difference in age, sex, return to the operating room, and discharge.

The use of topical TXA in GABC significantly reduced postoperative hemorrhage, packed cell volume, platelet transfusion, and FFP after surgery. Besides, it had no significant effect on the return to the operating room and mortality.

The use of topical TXA in GABC significantly reduced postoperative hemorrhage, packed cell volume, platelet transfusion, and FFP after surgery. Cyclopamine Besides, it had no significant effect on the return to the operating room and mortality.

Inadequate pain relief after thoracotomy may lead to postoperative respiratory complications.

We have compared total morphine consumption in 24 hours following thoracotomy.

This prospective randomized pilot study involved 50 patients undergoing elective thoracotomy for lung surgery at AIIMS, New Delhi.

Fifty patients undergoing elective thoracotomy were randomly allocated into two groups. In Group I patients, ultrasound (USG)-guided paravertebral catheter was inserted preoperatively and in Group II patients, serratus anterior plane (SAP) catheter was inserted by the surgeon before closure. Ropivacaine bolus (group I 0.2% 0.1 ml/kg and group II 0.375% 0.4 ml/kg) was given before extubation, followed by its continuous infusion for 24 hours. If the numerical rating scale (NRS) was >3, then patients were given intravenous (i.v.) morphine 3 mg. Total 24-hour morphine consumption, duration of effective analgesia, hemodynamic parameters, side effects, and overall patient satisfaction were recorded.

T-test was used to compare the parametric values in both the groups, whereas the Mann-Whitney U-test was performed to compare the nonparametric values.

Postoperative morphine requirement in the ParaVertebral Block (PVB) group (8.65 ± 4.27 mg) was less as compared to the SAP group (11.87 ± 6.22 mg) but that was not statistically significant (

0.052). Postoperative pain scores at rest and on movement, patient satisfaction, and incidence of chronic post-thoracotomy pain were comparable in both the groups.

SAP block with continuous catheter technique seems to be a safe and effective modality for the management of acute postoperative pain after thoracotomy.

SAP block with continuous catheter technique seems to be a safe and effective modality for the management of acute postoperative pain after thoracotomy.

Dietary factors play an important role in the development of depressive symptoms. Carotenoids have effective antioxidant and anti-inflammatory effects, but few studies have explored the associations between dietary carotenoid intake and depressive symptoms.

To evaluate the association between dietary carotenoid intake and the risk of depressive symptoms in adults from the United States.

This cross-sectional study included adult participants from the National Health and Nutrition Examination Survey 2009-2016. Depressive symptoms were assessed using the Patients’ Health Questionnaire-9. Intake of carotenoids was obtained through two 24-h dietary recall interviews. We applied logistic regression models and restricted cubic spline models to evaluate the associations of dietary alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein with zeaxanthin, and total carotenoid intake with the risk of depressive symptoms.

Overall, a total of 17,401 adults aged 18-80 years were included in this study. After adjustment for potential confounders, the odds ratios (95% confidence intervals) of depressive symptoms in the highest versus lowest quartiles were 0.