Activity

Standardized uptake value (SUV) normalized by lean body mass ([LBM] SUL) is recommended as metric by PERCIST 1.0. The James predictive equation (PE) is a frequently used formula for LBM estimation, but may cause substantial error for an individual. The purpose of this study was to introduce a novel and reliable method for estimating LBM by limited-coverage (LC) CT images from PET/CT examinations and test its validity, then to analyse whether SUV normalised by LC-based LBM could change the PERCIST 1.0 response classifications, based on LBM estimated by the James PE.

First, 199 patients who received whole-body PET/CT examinations were retrospectively retrieved. A patient-specific LBM equation was developed based on the relationship between LC fat volumes (FV

) and whole-body fat mass (FM

). This equation was cross-validated with an independent sample of 97 patients who also received whole-body PET/CT examinations. Its results were compared with the measurement of LBM from whole-body CT (reference standard before and after treatment.

LBM algorithm-dependent variability in PERCIST 1.0 classification is a notable issue. SUV normalised by LC-based LBM could change PERCIST 1.0 response classifications based on LBM estimated by the James PE, especially for patients with a percentage variation of SUL

close to the threshold.

LBM algorithm-dependent variability in PERCIST 1.0 classification is a notable issue. SUV normalised by LC-based LBM could change PERCIST 1.0 response classifications based on LBM estimated by the James PE, especially for patients with a percentage variation of SULpeak close to the threshold.Comparability of specific behavioral skills in diverse animal species is of central importance in animal cognition. Yet, as the present analysis of “rescuing behavior” shows, the lack of validity analysis may lead to contradictory results.Large amounts of water-based drilling cuttings (WDC) would be generated during the drilling of shale gas wells, which would occupy land resources and pose significant threat to soil and groundwater environment. The aim of this study was to assess the feasibility of using WDC as a replacement of natural clay to prepare sintered bricks. To determine the optimum preparation condition, the weight loss on ignition, bulk density, water absorption, and compressive strength of the samples were tested. Meanwhile, the environmental performance of the final products was evaluated and micro-analysis was conducted via X-ray diffraction and scanning electron microscopy. The results showed that using WDC to manufacture sintered bricks was technically feasible, but the physical mechanical performance would significantly decrease with the increase of the replacement ratio because of the presence of less silica and excessive calcium. RO5126766 The addition of waste glass and fly ash could promote the generation of molten glassy phase and form the crystal particle bonding structure, which would contribute to the physical-mechanical performance of WDC sintered bricks. Some mineral components in raw materials decomposed and formed minerals with better thermal stability during the sintering process. Under the optimum preparation conditions (mass ratio of WDC waste glass fly ash at 402040, sintering temperature at 900 °C, and insulation time at 2 h), the physical-mechanical and environmental performance of WDC sintered bricks could meet the requirements of corresponding Chinese standards and ASTM standards. Thus, in this study, an effective solution to recycle WDC from shale gas development is provided.Little is known on the potential impact of temperature on respiratory morbidity, especially for children whose respiratory system can be more vulnerable to climate changes. In this time-series study, Poisson generalized additive models combined with distributed lag nonlinear models were used to assess the associations between ambient temperature and childhood respiratory morbidity. The impacts of extreme cold and hot temperatures were calculated as cumulative relative risks (cum.RRs) at the 1st and 99th temperature percentiles relative to the minimum morbidity temperature percentile. Attributable fractions of respiratory morbidity due to cold or heat were calculated for temperatures below or above the minimum morbidity temperature. Effect modifications by air pollution, age, and sex were assessed in stratified analyses. A total of 877,793 respiratory hospital visits of children under 14 years old between 2013 and 2017 were collected from Beijing Children’s Hospital. Overall, we observed J-shaped associations asthma hospital visits can be enhanced under higher level exposure to O3.It is known that the tailings of gold mines have brought serious heavy metal pollution; however, the heavy metal pollution caused by gold tailings in specific geological environments and extraction processes still must be studied. This study investigated the distribution, speciation, bioaccumulation, and pollution of heavy metals in soils from the Yueliangbao gold tailings area in central China, where gold was extracted by cyanidation. The results show that the concentrations of Cu, Pb, Zn, Mn, Mo, and Cd in the soils of the tailings pond were higher than those in the local background. The concentrations of heavy metals related to mineralization activities, such as Cu, Pb, Zn, and Mo, varied with the distance to the tailings pond center. There was a decreasing trend of tailings pond center > tailings pond entrance > surrounding environment. This study’s gold tailings pond differed from those of other regions because of its high content of unextracted Cu remaining in the pond. The proportion of non-residual Cu in the tailing pond soil was much higher than that of residual Cu, indicating it was likely to migrate to the surrounding environment. The pollution assessment indicated that the tailings pond soils were heavily polluted by Cu, and the level of heavy metal pollution in soils was positively correlated with the distance to the tailings pond center. Consequently, this tailings pond may become a source of Cu pollution in the surrounding environment, thus endangering environmental safety and human health. The study of heavy metal concentrations in the dominant plants showed that Chinese brake (Pteris vittata L.), Ramose scouring rush (Equisetum ramosissimum), and Manyflower silvergrass (Miscanthus floridulus) had the potential to be used for the phytostabilization of Cu.