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Ceroplastes cirripediformis Comstock is one of the most destructive invasive pests that have caused various negative impacts to agricultural, ornamental, and greenhouse plants. Since it is time- and labor-consuming to control C. cirripediformis, habitat evaluation of this pest may be the most cost-effective method for predicting its dispersal and avoiding its outbreaks. Here, we evaluated the effects of climatic variables on distribution patterns of C. cirripediformis and produced a global risk map for its outbreak under current and future climate scenarios using the Maximum Entropy (MaxEnt) model. Our results showed that mean temperature of driest quarter (Bio 9), precipitation of coldest quarter (Bio 19), precipitation of warmest quarter (Bio 18), and mean temperature of wettest quarter (Bio 8) were the main factors influencing the current modeled distribution of C. cirripediformis, respectively, contributing 41.9, 29.4, 18.8, and 7.9%. The models predicted that, globally, potential distribution of C. cirripediformis would be across most zoogeographical regions under both current and future climate scenarios. Moreover, in the future, both the total potential distribution region and its area of highly suitable habitat are expected to expand slightly in all representative concentration pathway scenarios. The information generated from this study will contribute to better identify the impacts of climate change upon C. cirripediformis’s potential distribution while also providing a scientific basis for forecasting insect pest spread and outbreaks. Furthermore, this study serves an early warning for the regions of potential distribution, predicted as highly suitable habitats for this pest, which could promote its prevention and control.

Studies have reported a protective relation to cognitive decline with long-term intake of total and individual dietary carotenoids. However, the underlying mechanisms have not yet been clearly established in humans.

To evaluate the prospective association between intakes of total and individual carotenoids and risk of incident Alzheimer dementia (AD) and explore the underlying neuropathological basis.

Among 927 participants from the Rush Memory and Aging Project who were free from AD at baseline and were followed up for a mean of 7 y, we estimated HRs for AD using Cox proportional hazards models by intakes of energy-adjusted carotenoids. click here Brain AD neuropathology was assessed in postmortem brain autopsies among 508 deceased participants. We used linear regression to assess the association of carotenoid intake with AD-related neuropathology.

Higher intake of total carotenoids was associated with substantially lower hazard of AD after controlling for age, sex, education, ApoE-ε4, participation in cognitiv, on AD incidence that may be related to the inhibition of brain β-amyloid deposition and fibril formation.

Our findings support a beneficial role of total carotenoid consumption, in particular lutein/zeaxanthin, on AD incidence that may be related to the inhibition of brain β-amyloid deposition and fibril formation.

Taste preference is an important determinant of dietary intake and is influenced by taste exposure in early life. However, data on dietary taste patterns in early childhood are scarce.

We aimed to evaluate dietary taste patterns in early childhood, to examine their tracking between the ages of 1 and 2 y, and to examine their associations with socioeconomic and lifestyle factors.

Dietary intake of children participating in a population-based cohort was assessed with a 211-item age-specific FFQ at the ages of 1 y ( n=3629) and 2 y (n =844) (2003-2007). Taste intensity values of FFQ food items were calculated based on a food taste database that had been previously constructed and evaluated using a trained adult sensory panel. Cluster analysis based on taste values identified 5 taste clusters that we named “neutral,” “sweet and sour,” “sweet and fat,” “fat,” and “salt, umami and fat.” Linear regression models were used to examine associations of percentage energy (E%) intake from these taste clusters with sildren are maternal sociodemographic factors and feeding practices.This trial was registered at trialregister.nl as NL6484.

Dietary taste patterns in this Dutch cohort were more varied and intense in taste at age 2 y than at 1 y, reaching a level similar to that previously observed in Dutch adults. Important factors related to dietary taste patterns of young children are maternal sociodemographic factors and feeding practices.This trial was registered at trialregister.nl as NL6484.Two novel, self-reporting distyryl BODIPY-based photodynamic therapy agents functionalized with singlet oxygen responsive imidazole and tertiary amine moieties are developed. Heavy atom-free photosensitizers are demonstrated to have efficient photodynamic action in MCF7 cells. The fluorescence intensity of the photosensitizers is shown to be reduced as a result of 1O2 generation without any significant change in photodynamic activity.Wound healing is a complex and sequential biological process that involves multiple stages. Current treatments for nonhealing or chronic wounds are unsatisfactory as they exert a single effect on one specific activity. Herein, we constructed a silver nanowire (AgNW)-based, three-dimensional (3D), porous foam dressing that is flexible and conductive. This conductive foam dressing was composed of AgNWs modified with a stable hydrophobic coating and porous polyurethane (PU), providing a skeleton to support the 3D conductive networks. The AgNWs-PU foam dressing exhibited favorable biocompatibility, outstanding electrical properties, excellent bending-compression durability, and long-term stability under wet conditions, making it suitable for wound treatment. Via the conductive foam dressing, negative pressure and exogenous wound directional electric fields (EFs) could be integrated for simultaneous implementation, and the artificial jointly constructed microenvironment promoted wound healing in a system. This novel “all-in-one” device presented intrinsic multifunctionality, including the drainage of pus and necrotic tissue, mitigation of inflammation, promotion of cell proliferation, direction of keratinocyte migration, and induction of angiogenesis. An immunohistochemical assay and western blot analysis illustrated that the angiogenesis and cell proliferation pathways in the tissue were significantly activated when this novel therapy was adopted. More importantly, the practical performance of this “all-in-one” device was demonstrated by assessment of full-thickness defect wounds in model pigs. Comparing the percentage of residual wound area after administration of traditional treatment (25.82 ± 3.52%) and the novel treatment (3.07 ± 1.23%) demonstrated the promising applications of this novel treatment in clinical wound healing.