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Empirical evidence is mounting that monitoring momentary experiences for the presence of early warning signals (EWS) may allow for personalized predictions of meaningful symptom shifts in psychopathology. Studies aiming to detect EWS require intensive longitudinal measurement designs that center on individuals undergoing change. We recommend that researchers (1) define criteria for relevant symptom shifts a priori to allow specific hypothesis testing, (2) balance the observation period length and high-frequency measurements with participant burden by testing ambitious designs with pilot studies, and (3) choose variables that are meaningful to their patient group and facilitate replication by others. Thoroughly considered designs are necessary to assess the promise of EWS as a clinical tool to detect, prevent, or encourage impending symptom changes in psychopathology.Six marine litter standing stock surveys were carried out to determine the influence of monsoon on the temporal abundance and composition of macro-litter in Mkomani beach, Mombasa Kenya. Foam (0.073 items m-2) and plastic (0.042 items m-2) fragments had the highest densities. The brand audit indicated that 66.9% of branded marine litter was of Kenyan origin. Food product packaging contributed 78.4% of the branded litter with PET bottles being the most abundant type of packaging (48.2%). Foreign products contributed 35.6% of branded marine litter during South East Monsoon (SEM) whereas only 11.7% during North-East Monsoon (NEM). Worth noting, PET packaging dominated during SEM (53.6%) compared to NEM (20.2%). Mkomani beach could be considered “extremely dirty” with a Clean-Coast Index greater than 20. The study concludes that monsoons influences litter diversity, richness and evenness.The prevalence of microplastics along the coastal habitats has become a global concern owing to the increased input of plastic debris from multiple sources. The present study is the first of its kind to examine the prevalence and distribution of microplastics in Odisha coast. The average microplastic abundance in the nine stations along Odisha coastal beach is 258.7 ± 90.0 particles/kg of beach sediment. Among the stations sampled, Swargadwara was reported with the highest microplastic abundance of 378.3 ± 39.7 particles/kg of beach sediment andAbhayachandpurwas found with the lowest number of 153.3 ± 27.3 particles/kg. Different types of microplastics varying in color, size, and shape were encountered in the study. From the Raman spectroscopic analysis, twelve types of polymers including High Density Polyethylene, Polystyrene, Polyvinyl chloride, and acrylonitrile copolymer were identified.Bio-based plastics were designed to replace single-use plastics and to cause less post-consumer environmental damage. This paper assesses the weathering of four bio-based polymers created by ring opening polymerization (ROP) promoted by a previously reported Ti-based catalyst, to detect any problems before production was scaled up. selleck chemicals llc Samples were aged in seawater to identify degradation products and monitor structural changes. Surfaces evidenced degradation and a range of leaching products was observed. Aside from compounds used in the preparation of the plastics (i.e. residual monomers and benzyl alcohol), the degradation products included carboxylic acids (often found in plastic leachate), oxacyclohexadecan-2-one (potentially toxic to aquatic life) and triphenylmethane (potential carcinogen). Overall, there were fewer structural changes in the fossil fuel based polymer (PS) and in the commercially available bio-based plastic studied for comparison purposes than the lab based bio-based polymers.Babesia rossi is the most pathogenic among the large canine babesias and it is the major cause of canine babesisosis in Nigeria. In South Africa it is transmitted by Haemaphysalis elliptica however, its putative vector in Nigeria where Rhipicephalus sanguineus is the most prevalent tick on dogs compared to Haemaphysalis species has not been ascertained. The incongruity between tick distribution and the frequent detection of B. rossi in Nigeria motivated this investigation to identify the local vector(s) of B. rossi. A total of 3805 ticks were collected from 363 naturally infested dogs from different parts of Nigeria. Of these numbers, 758 engorged female ticks; Rh. sanguineus (n = 660) and H. leachi (n = 98) were incubated for oviposition and hatching. After the completion of egg laying, Rh. sanguineus (n = 69) and H. leachi (n = 24) and their resulting progenies were screened for the presence of B. rossi DNA using a nested PCR targeting the 693 bp of the 18S rRNA gene of Babesia spp. Amplification and sequencing of B. rossi DNA was successful in the adults of H. leachi and their resulting egg and larval progenies but not in the adult Rh. sanguineus and progenies. The B. rossi DNA sequences from the H. leachi and their progenies have 99-100 % identity to each other and 98-99 % identical to sequences of B. rossi in GenBank (GenBank MH143395.1), thus confirming transovarian passage. This evidence confirms for the first time following the reclassification of H. leachi to H. elliptica in South Africa the role of H. leachi in the transmission of B. rossi in dogs in Nigeria.Free-ranging wild ungulates are widespread in Austria, and act as hosts (i.e. feeding hosts) for ticks, including Ixodes ricinus, and as reservoir hosts for pathogens transmitted by I. ricinus. Due to climate change, the abundance of I. ricinus might be increasing, which could potentially lead to higher prevalences of tick-borne pathogens, such as Babesia spp. and Anaplasma phagocytophilum, some known for their zoonotic potential. Human babesiosis is classified as an emerging zoonosis, but sufficient data of these parasites in central Austria is lacking. In order to assess the abundance of vector-borne pathogens, blood of roe deer (Capreolus capreolus; n = 137), red deer (Cervus elaphus; n = 37), mouflons (Ovis gmelini; n = 2) and chamois (Rupicapra rupicapra; n = 1), was collected and tested for pathogen DNA in two different sampling sites in central Austria. DNA of tick-borne pathogens was detected in 15.5 % (n = 27) of these animals. Babesia capreoli (n = 22 in roe deer; n = 1 in mouflon), Babesia divergens (n = 1, in red deer), and Anaplasma phagocytophilum (n = 4, in roe deer) were detected.