Holmes

Methyl transverse relaxation-optimized spectroscopy (TROSY)-based NMR, cryo-EM, and biochemical assays show that, on binding Bz-LL or covalent inhibitors, MtClpP1P2 undergoes a conformational change from an inactive compact state to an active extended structure that can be explained by a modified Monod-Wyman-Changeux model. Our study establishes a…[Read more]

When the Y. lipolytica A-101 was cultivated at optimized pH (5.0) using biofuel waste as a medium, the protein concentration was increased to 8.28-a 44% enhancement as compared to the original (3.65). This study has thus demonstrated a beneficial way to cultivate Y. lipolytica A-101 on biofuel waste for enhanced production of single cell protein…[Read more]

Temperate wetlands have been undergoing increased nitrogen (N) inputs in the past decades, yet its influence on dissolved organic carbon (DOC) dynamics is still elusive in these ecosystems. Here, using a field multi-level N addition (0, 6, 12, and 24 g N m-2 year-1) experiment, we investigated the changes in aboveground plant biomass, DOC…[Read more]