Broe

BACKGROUND Liver fibrosis is the primary cause of liver cirrhosis and hepatocellular carcinoma and leads to considerable morbidity and mortality. Recent studies have shown that microRNAs are associated with fibrotic processes in liver disorders, but the exact role of miR-202 is still unclear, and its related mechanisms are not fully understood.…[Read more]

of high implementation fidelity. However, team members expressed low confidence that Breathewell would be adopted and maintained post-trial. A potential explanation was weak alignment with several CFIR constructs, including tension for change, relative priority, and leadership engagement that contribute to organizational receptivity and motivation…[Read more]

CONCLUSION This study identified consistent characteristics of the intrinsic subtalar ligaments and clarifies the local anatomical situation. The dimensions and footprints of the intrinsic ligaments of the subtalar joint suggest a more important role of the CL and ACaL in the stability of the subtalar joint. Elesclomol The results of this study…[Read more]

Neural stem/progenitor cells (NSPCs) have a potential to treat various neurological diseases, such as Parkinson’s Disease, Alzheimer’s Disease and Spinal Cord Injury. However, the limitation of NSPCs sources and the difficulty to maintain their stemness or to differentiate them into specific therapeutic cells are the main hurdles for clinical…[Read more]

Copyright © 2020 Huangfu, Kim, Xu, Ning, Qin, Li and Li.(R)-1-phenyl-1,2-ethanediol is an important synthon for the preparation of β-adrenergic blocking agents. This study identified a (2R,3R)-butanediol dehydrogenase (KgBDH) from Kurthia gibsonii SC0312, which showed high enantioselectivity for production of (R)-1-phenyl-1,2-ethanediol by r…[Read more]