Mortensen

Hb A2 levels are usually high in carriers of β-thalassemia (β-thal). These levels also provide a sensitive marker for the identification of hemoglobin (Hb) variants. In this study, we aimed to examine two patients from two Chinese families who showed elevated Hb A2 levels but did not show any signs of β-thal. The HBB variants were analyzed us…[Read more]

Describing the prevalence of chronic diseases and associated socioeconomic and demographic factors, evaluating the patterns of social distancing and the antibodies prevalence against SARS-CoV-2 and COVID-19 symptoms in carriers and non-carriers of chronic diseases.

Data from 77,075 individuals aged 20 to 59 from three steps of the…[Read more]

Clinical signs of an infection of the hand can be subtle initially or in a chronic state. But even in a progressive stadium it might be difficult to define an involvement of soft tissue, joint or bone. This review article addresses the diagnostic options of radiologic imaging. Radiographs of the affected region are the basic diagnostics.…[Read more]

Bipolar disorder is a severe mental illness characterized by recurrent manic and depressive episodes. To better understand its genetic architecture, we analyze ultra-rare de novo mutations in 354 trios with bipolar disorder. Enzalutamide datasheet For germline de novo mutations, we find significant enrichment of loss-of-function mutations in…[Read more]

91, 95% CI 0.52-1.58, p=.74), myocardial infarction (OR 0.92, 95% CI 0.44-1.92, p=.83) and permanent pacemaker implantation (PPM) (OR 0.54, 95% CI 0.27-1.07, p=.08) between the two groups. During mid to long-term follow up (6-months to 5-years), there were no significant differences between ViV-TAVR and redo-SAVR for all-cause mortality,…[Read more]

Breast cancer (BC), a heterogeneous disease, features microRNA-related single nucleotide polymorphisms (miRSNPs) as underlying factors of BC development, thus providing targets for novel diagnostic and therapeutic strategies. This study investigated miRSNPs in BC susceptibility in Australian Caucasian women.

The study population included…[Read more]

Bacterioplankton are main drivers of biogeochemical cycles and important components of aquatic food webs. While sequencing-based studies have revealed how bacterioplankton communities are structured in time and space, relatively little is known about intraspecies diversity patterns and their ecological relevance. Here, we use the newly developed…[Read more]