Moser

This editorial provides a concise introduction to the methods and applications of inertial sensors. We briefly describe the main characteristics of inertial sensors and highlight the broad range of applications as well as the methodological challenges. Finally, for the reader’s guidance, we give a succinct overview of the papers included in this…[Read more]

Phosphodiesterases (PDEs) form a superfamily of enzymes that catalyze the hydrolysis of cyclic nucleotides adenosine 3’5′-cyclic monophosphate (cAMP) and guanosine 3’5′-cyclic monophosphate (cGMP) to their inactive 5′ monophosphates. cAMP plays a critical role as a second messenger in endocrine tissues, and activation of cAMP signaling has been…[Read more]

In particular, platinum drug treatment in colon and liver cancer cell lines down-regulated S484 phosphorylation of UBF1, which is an essential transcription factor responsible for ribosomal DNA transcription activation, implying that inhibition of ribosome biogenesis might be involved in the cytotoxic mechanism of platinum drugs. Collectively,…[Read more]

a care gap, and community stigma reduction may facilitate return. Future re-engagement research should include causal evaluation of identified factors.

Maladaptive immune responses contribute to the pathogenesis of many chronic lung diseases. Here, we tested hypotheses that CD4 and CD8 T-cell and monocyte phenotypes are associated with lung…[Read more]