Stevens

However, we found no evidence that mindfulness training is able to buffer the effects of psychological distress on healthy participants’ immune system. In order to detect these effects, should they exist, larger randomised trials will be required.Vitamin D deficiency is a candidate risk factor for a range of adverse health outcomes. In a…[Read more]

In contrast to previous research, greater negative emodiversity was related to more symptoms of depression and anxiety and more physical health symptoms. Greater negative emodiversity was only associated with one positive outcome better executive functioning. These findings illustrate inconsistencies across studies in whether negative emodiversity…[Read more]

18. Therefore the total cost of snakebite in the Brazilian Amazon was estimated to be almost than US$8 million in 2015. CONCLUSIONS The economic burden of snakebite in Brazilian Amazon is notably high. Snakebites cause loss of productivity through inpatient treatment or deaths. © The Author(s) 2020. Published by Oxford University Press on behalf…[Read more]

[This corrects the article DOI 10.1371/journal.pone.0229977.].Introduction To mitigate the recent nationwide shortage of intravenous opioids, we developed a standardized perioperative oral opioid guideline anchored with appropriate use of nonopioid analgesia, neuraxial and loco-regional techniques. We hypothesize that adoption of this new…[Read more]

Natural bioactive compounds have increasingly proved to be promising in evidence- or target-directed treatment or modification of a spectrum of diseases including cerebral ischemic stroke. Hydroxysafflor yellow A (HSYA), a major active component of the safflower plant, has drawn more interests in recent year for its multiple pharmacological…[Read more]

The cytosolic level of inorganic pyrophosphate (PPi) is finely regulated, with PPi hydrolyzed primarily by the vacuolar H+-pyrophosphatase (H+-PPase, VHP1/FUGU5/AVP1) and secondarily by five cytosolic soluble pyrophosphatases (sPPases; PPa1-PPa5) in Arabidopsis thaliana. Loss-of-function mutants of H+-PPase (fugu5s) have been reported to show…[Read more]