Lomholt

Therapeutic systems to induce reactive oxygen species (ROS) have received tremendous success in the research of tumor theranostics, but suffered daunting challenges in limited efficacy originating from low presence of reactants and reaction kinetics within cancer cells. Here, ferrous sulfide-embedded bovine serum albumin (FeS@BSA) nanoclusters, in…[Read more]

Osteoarthritis (OA) is characterized by irreversible cartilage degradation with very limited therapeutic interventions. Drug candidates targeted at prototypic players had limited success until now and systems based approaches might be necessary. Consequently, drug evaluation platforms should consider the biological complexity looking beyond…[Read more]

Anal stenosis (AS) is rare but a severe complication of anal surgery. Most often it develops after hemorrhoidectomy [1, 2]. Depending on the grade of stenosis it may be mild, moderate or severe. Most of the severe type stenosis require surgical anoplasty. There are several commonly used flap types such as Y-V, V-Y, lateral, diamond-shaped and…[Read more]

Severe emphysema with hyperinflation presents a therapeutic challenge. Inhaled medication has limited efficacy in individuals with mechanical constraints to the respiratory pump and impaired gas exchange. Lung volume reduction surgery (LVRS) reestablishes some semblance of normal physiology, resecting grossly expanded severely diseased tissue to…[Read more]