Dobson

The hepatic stellate cells (HSCs) play a significant role in the onset of liver fibrosis, which can be treated by the inhibition and reversal of HSC activation. The RNA interference-mediated TLR4 gene silencing might be a potential therapeutic approach for liver fibrosis. The crucial challenge in this method is the absence of an efficient delivery…[Read more]

05) in the diets without CA (dEB ×CA; p less then .001). Dietary CA increased maltase activity and reduced the number of Ki67-positive cells (p less then .05). Increasing dEB values in diets without CA increased sucrose and lactase activities (quadratic; p less then .05), but no such effect was observed in the diets with CA (dEB ×CA; p less then .…[Read more]

Topographic steering has been observed around Gran Canaria, a high-profile circular island located in the Canary Island Archipelago, Spain, culminating in a complex lee-side wind regime at the Maspalomas dunefield. Maspalomas has experienced rapid environmental changes since the 1960s, coincident with a boom in the tourism industry in the region…[Read more]

Self-regulation, a social-cognitive process at the intersection of metacognition, motivation, and behavior, encompasses how people conceptualize, strive for, and accomplish their goals. Self-regulation is critical for behavioral change regardless of the context. Research indicates that self-regulation is learned. Integral to successful…[Read more]