Barry

To establish whether 4-nitroquinoline N-oxide-induced carcinogenesis mirrors the heterogeneity of human oral squamous cell carcinoma (OSCC), we have performed genomic analysis of mouse tongue lesions. The mutational signatures of human and mouse OSCC overlap extensively. Mutational burden is higher in moderate dysplasias and invasive SCCs than in…[Read more]

In this review, we briefly summarize recent advances in the development of Cu diffusion-proof materials, including metals, metal alloys, self-assembled molecular layers (SAMs), two-dimensional (2D) materials and high-entropy alloys (HEAs). Also, challenges are highlighted and future research directions are suggested.(1) Background Standard…[Read more]

Level of significance was set at p < 0.05.

LST partially explained the association between training volume and aBMD in all body segments upper limbs (58.37%; β = 0.00142), lower limbs (28.35%; β = 0.00156), spine (33.80%; β = 0.00124), and whole body (41.82%, β = 0.00131). There was no direct effect of training volume on aBMD in upper…[Read more]

Embryonal tumors are the new nomenclature of the primitive neuroectodermal tumors or PNET. Their supratentorial location and their manifestation in adult population are not very frequent. Embryonal tumors are conformed from undifferentiated neuroepithelial cells that have the ability to show differentiation to several cell lines. Next is presented…[Read more]

itical individuals have more extended SCC representations for blame in the context of self-agency.We explored the genetic architecture of metabolic risk factors of cardiovascular diseases (CVDs) and their clustering in Chinese boys and girls. Seven metabolic traits (body mass index [BMI], waist circumference [WC], systolic blood pressure [SBP],…[Read more]

Traditional Chinese medicine injections (TCMJ) used in the treatment of severe pneumonia have been widely implemented in clinical practice, but their overall efficacy and safety remain unclear. This paper aims to evaluate the efficacy and safety of TCMJ in the treatment of severe pneumonia.

PubMed, EMbase, Cochrane Library, Web of Science,…[Read more]

In this review, we highlight the recent progress of ACPPs for biomedical application based on different types of organic building blocks including photosensitizers, chemical drugs, and biomolecules. Moreover, the prospects and challenges of ACPPs for clinical application are also discussed. We hope this review entitled “Recent development of…[Read more]

Mechanistically, miR-31-5p antagomir activated AMPKα to exert the protective effects that were abrogated by AMPKα inhibition. Further studies revealed that Cab39 was required for AMPKα activation and pulmonary protection by miR-31-5p antagomir. We provide the evidence that endogenous miR-31-5p is a key pathogenic factor for inflammation and ox…[Read more]

0390, 0.0524, 0.0351, and 0.0374 cm, respectively. In addition, the linear attenuation coefficient (µ) for these materials were 17.77, 13.20, 19.71, and 18.5 cm-1, respectively. The findings indicate that nano-structured samples are more effective in the attenuation of X-ray energy. The nano-structured WO3 prototype was nearly 34% more efficient…[Read more]

d BP after delivery, and both might affect the future cardiovascular risk of these women.

We hypothesized that discharge SBP had different associations with outcomes in non-HFrEF (left ventricular ejection fraction ≥40%) patients with or without high blood pressure (HBP) at admission.

Non-HFrEF patients hospitalized for decompensated h…[Read more]