Activity

Postmenopausal osteoporosis is a frequent clinical condition which affects nearly 1 in 3 women. Estrogen deficiency leads to rapid bone loss which is maximal within the first 2-3 years after the menopause transition and can be prevented by menopause hormone therapy (MHT). Not only, MHT prevents bone loss and the degradation of the bone microarchitecture but it significantly reduces the risk of fracture at all bone sites by 20-40%. It is the only anti-osteoporotic therapy that has a proven efficacy regardless of basal level of risk, even in low-risk women for fracture. Following the publication of the WHI results, use of MHT has considerably declined due to safety concerns which raise the question as to whether it might still be used in the prevention of osteoporosis. Over the last years, subsequent re-analyses of the WHI and further trials have challenged the initial conclusions of the WHI. It is now clearer that the individual benefit-risk balance of MHT is dependent on the individual risk profile in each woracture.

During episodes of low cardiac output, sympathetic neurohumoral responses with peripheral vasoconstriction result in an increase in the core-peripheral temperature gradient (CPTG). Selleckchem Nafamostat However, assessment of CPTG as a surrogate of low cardiac output and a predictor of outcomes in pediatric cardiac patients rarely has been performed. In this retrospective study, the authors assessed the prognostic abilities of CPTG, skin temperature, and serum lactate level for predicting clinical outcomes.

A retrospective single-center study.

Referral high-volume pediatric center.

Patients younger than four months of age with congenital heart disease who underwent cardiac surgery with cardiopulmonary bypass.

None.

The primary outcome was a composite of one or more of the following major adverse events (MAEs) that occurred within seven days after surgery death from any cause, cardiac arrest, emergency chest reopening, and requirement for extracorporeal membrane oxygenation. A total of 661 patients were included in the d skin temperature had low performance for prediction of MAEs in children after cardiac surgery. Either of those markers, especially at admission, should not be used as a single marker for assessing the condition of a patient.

Speaking a second language influences jitter and shimmer when comparing monolingual English speakers with bilingual English-Spanish speakers. However, there is little information about differences on voice acoustic parameters when comparing monolingual Spanish speakers with bilingual Spanish-English speakers during their productions in Spanish.

Determine differences in five voice acoustic parameters commonly used in voice assessments (fundamental frequency, jitter, shimmer, Harmonics-to-Noise Ratio and Cepstral Peak Prominence Smoothed) which may be influenced by bilingualism.

Exploratory cross-sectional study with two groups of female participants monolingual Spanish speakers (n=17), and bilingual Spanish-English speakers (n=11). Participants filled out a questionnaire and recorded two voice samples (sustained vowel /a/ and reading). For this study, all the participants reported that their native language was Spanish.

Being a female bilingual speaker had a significant effect on Shimmer (%) with a Beta=-0.7. Similar tendency was found on harmonics-to-noise ratio (B=0.2) and cepstral peak prominence smoothed (B=0.2).

Our results indicate that being a native Spanish female speaker, speaking English as a second language, has significant small effects on voice acoustic parameters, such as shimmer, harmonics-to-noise ratio and cepstral peak prominence smoothed, during their productions in Spanish. This information is of interest for assessment and intervention plans of bilingual speakers at clinical and work-related settings.

Our results indicate that being a native Spanish female speaker, speaking English as a second language, has significant small effects on voice acoustic parameters, such as shimmer, harmonics-to-noise ratio and cepstral peak prominence smoothed, during their productions in Spanish. This information is of interest for assessment and intervention plans of bilingual speakers at clinical and work-related settings.

This study aimed to assess the efficacy of Kinesio taping on male patients with mutational falsetto undergoing voice therapy.

Double blind, randomized, sham-controlled clinical trial.

Interviews were conducted with thirty seven mutational falsetto patients. Included 32 participants were randomized and divided into two groups. Two were dropped out due to irregular attendance, 30 participants were included in final analysis.

The study group was treated with voice therapy and applications of three different therapeutic Kinesio taping techniques with seven Kinesio tapes four times over two weeks, and the control group was treated with voice therapy, and applied to sham Kinesio taping.

The values of fundamental frequency, jitter, shimmer, noise-harmonic ratio, maximum phonation time, Voice Handicap Index-10 scores, and Grade-Roughness-Breathiness-Asthenia-Strain Scale scores were recorded at the baseline and after the two weeks.

There were significant differences between the study group and the control group with respect to the values of fundamental frequency (P=0.011), jitter (P=0.041), shimmer (P=0.036), noise-harmonic ratio (P=0.003), maximum phonation time (P ≤ 0.001), Voice Handicap Index-10 scores (P=0.036), and Grade-Roughness-Breathiness-Asthenia-Strain Scale scores (P=0.007; P ≤ 0.021; P=0.022; P=0.002; P=0.021, respectively) at the end of the study.

The study demonstrated that Kinesio taping with voice therapy is an efficient and effective technique for treating mutational falsetto patients.

The study demonstrated that Kinesio taping with voice therapy is an efficient and effective technique for treating mutational falsetto patients.

Critically ill patients often experience coexisting symptoms. Thirst, in particular, appears to be an important symptom, having the highest prevalence, intensity, and induction of distress, and is significantly correlated with other symptoms. However, thirst and dry mouth are not usually assessed or treated.

The aim of the study was to demonstrate the effectiveness of an intervention bundle to relieve thirst and dry mouth.

The present study was a randomised controlled trial in which critically ill patients were allocated to an experimental or control group. The intervention bundles, including vitamin C sprays, peppermint water mouthwash, and a lip moisturiser, were provided to the experimental group for 3days, whereas patients in the control group were exposed to the placebo interventions, including saline sprays, 40°C water mouthwash, and wetting the lips with water.

A total of 61 patients were recruited to the study; 65.6% (n=41) were men, and the average age was 64.2±16.8 years. The average decrease in thirst intensity and oral mucosa situation scores after the interventions was larger in the experimental group patients relative to controls (1.