Holmes

  • Holmes posted an update 7 months, 1 week ago

    This was mainly because of the maintenance of the columnar grain morphology even after solution treatment. In addition, the formation of M6C carbides, Y2O3, and SiO2 improved creep life. To summarize the effect of Y, Y addition promoted the formation of cracks, which brought about creep anisotropy; however, it improved creep properties through the…[Read more]

  • Holmes posted an update 7 months, 1 week ago

    Given the potential off-target effects associated with the administration of traditional therapeutics (for example, monoclonal antibodies, small molecule inhibitors), we highlight the opportunity for nanomedicine in macrophage phagocytosis intervention.Antibiotic-resistant bacteria are a major global health threat that continues to rise due to a…[Read more]

  • Holmes posted an update 7 months, 1 week ago

    ance rank estimation in the presence of non-additive interactions.

    Nesting in large aggregations provides several important advantages for colonially breeding birds. However, it also imposes certain costs, associated with facilitated pathogen transmission and social stress. The cost-benefit ratio is not similar for all the birds in a colony…[Read more]

  • Holmes posted an update 7 months, 2 weeks ago

    Brain weights following behavioral testing did not differ. The results reported here along with existing literature suggest sevoflurane is largely without effects on later cognition in adult rodents when exposure is of a relatively short duration and at a relatively low concentration.Quantitative reverse transcription polymerase chain reaction…[Read more]

  • Holmes posted an update 7 months, 2 weeks ago

    Under specific circumstances, a commercially available CDS tool was used in partnership with a private payer and a radiology benefits management company to expedite prior authorization of outpatient advanced imaging examination orders deemed likely to be appropriate by multispecialty professional guidelines.Abnormal human trabecular meshwork (HTM)…[Read more]

  • Holmes posted an update 7 months, 2 weeks ago

    Dynamic consent has been proposed as a process through which participants and patients can gain more control over how their data and samples, donated for biomedical research, are used, resulting in greater trust in researchers. It is also a way to respond to evolving data protection frameworks and new legislation. Others argue that the broad…[Read more]

  • Holmes posted an update 7 months, 2 weeks ago

    The aim of this work was to review studies in which genetic variants were assessed with respect to metabolic response to treatment with novel glucose-lowering drugs dipeptidyl peptidase-4 inhibitors (DPP-4i), glucagon-like peptide-1 receptor agonists (GLP-1 RA) and sodium-glucose cotransporter 2 inhibitors (SGLT2i). In total, 22 studies were…[Read more]

  • Holmes became a registered member 7 months, 2 weeks ago

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