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03, 0.09)] and infancy period [β 0.04 (95% CI 0.00, 0.07)] had more sleep problems. Children of mothers drinking ≥1 glass of alcohol a day around 14 weeks of gestation had a 2 points higher sleep problem score [β 2.55 (95% CI 0.21, 4.89)] and children of mothers smoking ≥1 cigarette per day in that period had a one point higher score [β 1.07 (95% CI 0.10, 2.03)]. Infants with relative weight loss (delta BMI-SD) had a higher sleep problem score during childhood [β -0.32 (95%CI -0.60, -0.04)]. CONCLUSIONS We identified several potential determinants during pregnancy and infancy associated with childhood sleeping problems. We encourage further research into these and other potential determinants to replicate results and to identify underlying mechanisms. OBJECTIVES Little is known about the experiences of therapists delivering psychotherapy for patients with dissociative seizures (DS), a complex disorder associated with a range of comorbid psychosocial and mental health difficulties. #link# This study set out to explore therapists’ experiences of delivering DS-specific, manualized cognitive behavioral therapy (CBT) to adults with DS within the context of a randomized control trial. METHODS Interviews were conducted with 12 therapists involved in the COgnitive behavioral therapy vs standardized medical care for adults with Dissociative non-Epileptic Seizures (CODES) trial and were analyzed using thematic framework analysis (TFA). RESULTS Six main themes emerged, namely 1) aspects of the intervention that were favored, while others were not always considered applicable; 2) multiple and complex difficulties faced by patients; 3) working effectively within the protocol; 4) limitations of the protocol; 5) significance of formulation; and 6) quality of standardized medicance of working with complex patients should be considered when applying the intervention to individual cases. Setting the CBT intervention in the context of a structured care pathway involving neurology and psychiatry may facilitate the therapeutic process. A burgeoning body of literature suggests that poor childhood health leads to adverse health outcomes, lower educational attainment and weaker labour market outcomes in adulthood. We focus on an important but under-researched topic, which is the role played by infection-related hospitalization (IRH) in childhood and its links to labour market outcomes later in life. The participants aged 24-30 years in 2001 N = 1706 were drawn from the Young Finns Study, which includes comprehensive registry data on IRHs in childhood at ages 0-18 years. These data are linked to longitudinal registry information on labour market outcomes (2001-2012) and parental background (1980). The estimations were performed using ordinary least squares (OLS). The results showed that having an additional IRH is associated with lower log earnings (b = -0.110, 95 % confidence interval (CI) -0.193; -0.026), fewer years of being employed (b = -0.018, 95 % CI -0.031; -0.005), a higher probability of receiving any social income transfers (b = 0.012, 95 % CI -0.002; 0.026) and larger social income transfers, conditional on receiving any (b = 0.085, 95 % CI 0.025; 0.145). IRHs are negatively linked to human capital accumulation, which explains a considerable part of the observed associations between IRHs and labour market outcomes. We did not find support for the hypothesis that adult health mediates the link. Based on almost 5.000 direct observations on National Identification Cards, this paper offers the first estimation of the evolution of average heights in the city of La Paz (Bolivia) for the decades 1880s-1920s. The analysis focuses on men of middle and upper classes aged 19-50 years old. Despite the city’s growing economic importance and modernization, average heights remained stagnant around 163 cm. It also stands out that whereas average height differences between professional and ethnic groups remained significant and persistent throughout time, average heights remained stagnant in all groups. Three main reasons are provided to explain these inequalities between groups and stagnation across groups scarce improvements in agricultural production, increasing wage inequalities and the persistence of a bad disease environment. PURPOSE We aimed to explore whether WeChat app-based education and rehabilitation program (WERP) affected anxiety, depression, quality of life (QoL), loss of follow-up and survival profiles in non-small cell lung cancer (NSCLC) patients after undergoing surgical resection. METHODS 200 NSCLC patients who underwent surgical resection were randomly allocated to WERP group or control group at a 11 ratio and underwent a 12-month interventional stage and 48-month non-interventional follow-up stage. Anxiety and depression were evaluated by Hospital Anxiety and Depression Scale (HADS), and QoL was assessed by European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30). Loss of follow-up and survival data were also evaluated. RESULTS After the 12-month intervention (M12), HADS-anxiety score (5.00 ± 2.84 vs. 6.69 ± 4.01) and anxiety rate (19.0% vs. 41.0%) were lower in WERP group compared with control group; meanwhile, HADS-depression score (5.22 ± 2.77 vs. 6.55 ± 3.42) and depression rate (20.0% vs. 36.0%) were decreased in WERP group compared with the control group. Regarding click here at M12, the QLQ-C30 global health status score (74.44 ± 12.06 vs. 70.26 ± 17.29) and functional score (77.15 ± 15.00 vs. 71.40 ± 17.02) were higher, while QLQ-C30 symptom score was similar (27.29 ± 11.72 vs. 27.86 ± 12.69) in WERP group compared with the control group. Besides, both the 12-month loss to follow-up (3.0% vs 10.0%) and 60-month loss to follow-up (10.0% vs 20.0%) were less in WERP group than the control group. However, limited survival benefit of WERP was observed compared with the control group. CONCLUSIONS WERP is an effective way to improve well-being and quality of life in NSCLC patients after undergoing surgical resection. There is an increasing trend of developing various low-cost biogenic sorbents for the efficient and economical removal of noxious metals . Curry leaf powder (CLP), a promising non-toxic biosorbent containing several bioactive compounds was prepared by the pulverization of the dried leaves for the effective removal of Lead (Pb) and Cadmium (Cd). Various batch sorption experiments were carried out under constant temperature (25 °C), different pH (4.5-10.5), initial concentrations (50-200 mg L-1), adsorbent dosages (0.10-0.40 g) and contact times (0-60 min) to understand the optimum experimental conditions and simultaneously evaluate the adsorption isotherms and removal kinetics of CLP. Adsorption equilibrium was established in less than an hour interval (50 min). The pseudo-equilibrium process was best described by the pseudo-second-order kinetic (R2 ≥ 0.99), Freundlich and Langmuir isotherm model (R2 ≥ 0.94). The removal rate of Pb and Cd gradually increased (15.7 and 12.7 mg g-1 for Pb and Cd) at 100 mg L-1 of initial concentration till 60 min of contact period in a single contaminant system, the effect was non-significant for multiple adsorbent dosage systems (p > 0.