Bachmann

RESULTS CDNC24, like alphaxalone and propofol, caused dose-dependent hypnosis in vivo, with a higher therapeutic index. CDNC24 and alphaxalone, unlike propofol, did not cause developmental neuroapoptosis in the subiculum and mPFC. Propofol potentiated post- and extrasynaptic GABAA currents as evidenced by increased spontaneous inhibitory…[Read more]

Given the potentially devastating consequence of a single attack of NMOSD, caution is advised with IST discontinuation, particularly in patients with severe attack before IST.

IST discontinuation may increase the risk of relapse in seropositive patients with NMOSD even after 5 years of remission. Given the potentially devastating consequence of…[Read more]

Moreover, the fluctuation in vegetation is more related to precipitation variation since 1999. (2) Most areas recovered in the greening trend of the first period starting in 2009, occurring in 28.7% (2628 of 9148) of the total area. (3) The revegetated areas have a low PT and a high CVvi, that is, the revegetated areas need a long time to recover…[Read more]

The novel molecularly imprinted microspheres for four phenylarsonic compounds have been firstly prepared with the reversible addition-fragmentation chain transfer polymerization in a suspension system. The resulting polymeric microspheres were characterized by infrared spectrum, scanning electron microscope and differential scanning calorimetry.…[Read more]

Immunohistochemical staining and TUNEL apoptosis staining showed that TCI633 could effectively increase the expression of type II collagen and reduce the amount of chondrocyte apoptosis in cartilage. Therefore, the present study demonstrated that oral intake of TCI633 could significantly suppressing pain behavior, reduce joint swelling and…[Read more]

Heart failure (HF) and cardiac hypertrophy is an unfavorable outcome of pathological cardiac remodeling and represents the most important contributing factor for HF and cardiac hypertrophy. Amygdalin (AMG) is a cyanogenic glycoside derived from bitter almonds. Accumulating evidences have highlighted their pharmacological potentials against various…[Read more]

The objective of this study was to examine the effect of fatigue on maximal and rapid force capacities and muscular activation of the knee extensors and flexors. Seventeen professional soccer players volunteered to participate in this study. Peak torque (Tpeak) and rate of torque development (RTD) of knee flexor (90°. s-1, -30°. s-1) and e…[Read more]

Health policy pundits often observe that COVID-19 exposes healthcare’s grave deficiencies, inequities and underdeveloped capacities – factors hobbling Canada’s COVID-19 pandemic response. This issue of Healthcare Quarterly explores some of these weaknesses, illuminating systemic problems that persist despite the cascading damage they cause. It…[Read more]