Activity

These findings suggest that resveratrol enhances the efficacy of azoles and provides a promising application in therapy of C. albicans infection.Social influence is an important determinant of adolescent risk-taking, but little is known about how social norms contribute to adolescents’ tendency to recommend and engage in risky behaviours. Using the Adolescent Risk-taking Questionnaire, we assessed subjects’ (n = 198, age = 10-26) propensity to engage in and recommend risk-taking as well as their perception of risk norms. Adolescents recommended risk-taking more often compared to children and young adults. Perceived social norms were the most important factor predicting engagement in risky behaviours, and adolescents perceived risk-taking to be more normative than children or adults. Our findings highlight two mechanisms that contribute to adolescent risk-taking, active recommendation and perceived social norms. On this basis, we discuss potential means to attenuate excessive adolescent risk-taking.Females may adjust prenatal allocation in relation to ecological conditions that affect reproductive success, such as weather conditions or predation risk. In cooperative breeders, helpers might also influence reproductive success, and previous studies suggest that females can lay smaller eggs or larger clutches when breeding with more helpers. Although recent work suggests that helper effects can vary according to climatic variables, how social and ecological factors interact to shape prenatal allocation is poorly understood. Here, we examine how ecological and social components of the breeding environment covary with egg mass and clutch size, using as a model the sociable weaver Philetairus socius, a colonial, cooperatively breeding passerine. The study spanned 9 years and included over 1,900 eggs from over 550 clutches. Our analyses combined natural variation in weather conditions (rainfall before each reproductive event) with a nest predator-exclusion experiment and continuous monitoring of the mother’s she presence/absence of helper effects is modulated by rainfall levels or predation risk. These results challenge our current knowledge on some of the possible benefits of breeding with helpers and call for more long-term analyses on reproductive allocation adjustments in other cooperative systems.Parental abduction of a child occurs when the child is removed, by one parent, from the custody of the other parent or legally appointed guardians. The absence of the child has a profound impact on family members and significantly affects their lives. Talazoparib solubility dmso Also, parental abduction of a child is a relevant social problem which calls for further understanding. The aim of this research was to characterize the experiences of left behind parents in the context of parental abduction of a child. The data for this exploratory qualitative study were analyzed through thematic analysis of the semi-structured interviews carried out with eight male participants in Portugal. Participants’ perceptions were organized around three main themes the impact of this adverse event on different areas of their lives, recovery strategies, and perspectives regarding the future. Findings and their implications for professionals working with these families are discussed in light of the ambiguous loss and ambiguous boundaries frameworks.Diatoms are unicellular organisms containing red algal-derived plastids that probably originated as result of serial endosymbioses between an ancestral heterotrophic organism and a red alga or cryptophyta algae from which has only the chloroplast left. Diatom mitochondria are thus believed to derive from the exosymbiont. Unlike animals and fungi, diatoms seem to contain ancestral respiratory chains. In support of this, genes encoding gamma type carbonic anhydrases (CAs) whose products were shown to be intrinsic complex I subunits in plants, Euglena and Acanthamoeba were found in diatoms, a representative of Stramenopiles. In this work, we experimentally show that mitochondrial complex I in diatoms is a large complex containing gamma type CA subunits, supporting an ancestral origin. By using a bioinformatic approach, a complex I integrated CA domain with heterotrimeric subunit composition is proposed.Among current state-of-the-art estimation methods for multilevel IRT models, the two-stage divide-and-conquer strategy has practical advantages, such as clearer definition of factors, convenience for secondary data analysis, convenience for model calibration and fit evaluation, and avoidance of improper solutions. However, various studies have shown that, under the two-stage framework, ignoring measurement error in the dependent variable in stage II leads to incorrect statistical inferences. To this end, we proposed a novel method to correct both measurement bias and measurement error of latent trait estimates from stage I in the stage II estimation. In this paper, the HO-IRT model is considered as the measurement model, and a linear mixed effects model on overall (i.e., higher-order) abilities is considered as the structural model. The performance of the proposed correction method is illustrated and compared via a simulation study and a real data example using the National Educational Longitudinal Survey data (NELS 88). Results indicate that structural parameters can be recovered better after correcting measurement biases and errors.

How people deal with ridicule and being laughed at plays a role in romantic life. We extend the research on the fear of being laughed at (gelotophobia), joy in being laughed at (gelotophilia), and joy in laughing at others (katagelasticism) by testing their associations with romantic jealousy and its consequences for relationship satisfaction (RS).

Our study is based on Actor-Partner Interdependence Model (APIM) analyses of self and partner ratings of the laughter-related dispositions using data from 228 opposite-sex couples. APIM mediation analyses estimated indirect effects of jealousy on the associations between the dispositions and RS.

As expected, gelotophobia-related positively to jealousy in actors, whereas gelotophilia and katagelasticism showed differential relationships. The analysis of partner effects showed that the actual expressions in the dispositions are unrelated to jealousy but perceived expressions account robustly for experiences of jealousy beyond self-ratings. Finally, jealousy had indirect effects on the associations between the dispositions and RS.