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The present study involved enhancement of Meloxicam (MX) oral absorption for rapid onset of therapeutic action. A challenging approach using hot-melt-extrusion technique (HME) for production of stable novel preparation of MX pellets was successfully proposed.

Manipulating HME processing parameters (barrel-temperatures and screw-speed) and…[Read more]

in conclusion, the present meta-analysis suggested that dietary protein intake did not show a significant effect on the risk of UC or CD.

in conclusion, the present meta-analysis suggested that dietary protein intake did not show a significant effect on the risk of UC or CD.

there are no clarified non-invasive methods to evaluate small…[Read more]

To assess the variation in the waiting time for diagnostic imaging (DI) services among Croatian public hospitals and the utilization of computed tomography (CT) and magnetic resonance imaging (MRI) scanners.

We analyzed aggregated data from public hospitals. Counties were classified according to economic strength, and utilization was…[Read more]

re, recommendations for future research are proposed.Organisms living in high altitude must adapt to environmental conditions with hypoxia and low temperature, e.g. by changes in the structure and function of proteins associated with oxidative phosphorylation in mitochondria. Here we analysed the signs of adaptive evolution in 27 mitogenomes of…[Read more]

To explore the applicability of RigiScan monitoring data in the diagnosis of ED in the plateau area and evaluation of clinical therapeutic effects.

This study included 586 outpatients and inpatients with ED, aged 18－48 (mean 24.6) years, all confirmed according to the scores on the 5-item version of the International Index of Erectile F…[Read more]

Molybdenum (Mo) is an emerging contaminant in the environment. To assess the mobility and availability of Mo in soils, this study investigated the effect of soil properties on the sorption and desorption of Mo in soils. The Mo K-edge X-ray absorption near edge structure (XANES) of the soils after Mo sorption showed that sorbed molybdate was the…[Read more]

The benefit of

cardiac resynchronisation therapy (CRT) implantation in selected patients with heart failure is well known. The number of upgrade procedures is increasing but data on clinical response and outcome are less well documented as compared to

implantation.

To investigate the efficacy and outcome of CRT upgrade procedures…[Read more]