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LIMITATIONS All assessments were retrospective, so estimates of prevalence rates and especially exact AAO of some comorbidities are at risk of recall bias. CONCLUSIONS Sex and BD subtype are associated with different rates of comorbid disorders. However, there were minimal between group differences in median AAO of comorbidities. By describing the chronological sequence of comorbidities in BD we were able to demonstrate that a minority of comorbidities typically occurred post-onset of BD. This is noteworthy as these disorders might be amenable to interventions aimed at early secondary prevention. BACKGROUND About 1.4 million adults in North Carolina (NC) have mental illnesses. Many get no treatment because of mental health care provider shortages. Necessary prevention requires identification of covariates of mental illness. STUDY OBJECTIVE We tested the hypotheses There is no difference in adulthood mental health of the ACE-affected and the unaffected; ACEs do not significantly predict adulthood mental health. METHODS ACEs studied were living with a mentally ill person, an alcoholic, or drug abuser; witnessing violence; having divorced or unmarried parents; and being physically, mentally or sexually abused. We used data from 2012 and 2014 NC Behavioral Risk Factor Surveillance System. We had 19,187 observations with about 13,900 including ACE data. We conducted t- and χ2 tests of mental health differences between ACE-affected and unaffected and regression analysis to determine mental health predictors. RESULTS ACE distribution was 26.2% had parents or adults swearing at- or insulting them; 25% had divorced or unmarried parents; 22.6% lived with an alcoholic; 15.7% witnessed their parents beat each other; 13.8% lived with a mentally ill person; and 13.6% were hit or beaten by an adult in the home. Respondents also reported being touched sexually (9.4%); living with an adult who abused drugs (7.9%); and 4.1% were forced to have sex. The ACE-affected experienced significantly (p  less then  0.001) more days of poor mental health and had a higher likelihood of depression diagnosis than the unaffected. ACEs are statistically significant predictors of poor mental health in adulthood. V.BACKGROUND Patients with Borderline Personality Disorder (BPD) are characterized by impoverished self-regulatory mechanisms and self-image distortions. An intriguing question is to what extent BPD individuals develop accurate perceptions of their self-regulatory everyday functioning. Here, we tackle this issue evaluating their metacognitive abilities. Combretastatin A4 manufacturer METHODS One hundred and forty-four participants were enrolled in the study and divided into a BPD group and a healthy Control group, with each consisting of 36 participants paired with their corresponding close relatives. We compared self-report evaluations of the participants’ self-regulatory processes in daily-life activities and personality traits with external perceptions by close relatives, as a measure of metacognition. The ratings from participants and their informants were compared using an ANCOVA profile analysis. RESULTS Self-report results showed poor self-regulation ability in the daily environment as well as extreme scores in personality-traits in the BPD group in comparison with healthy participants. Further, in the BPD group we found a clear discrepancy between the information provided by patients and their close relatives regarding the processes involved in self-regulation of daily-life activities (but not for personality traits). This discrepancy was related to their clinical status and was not observed in the healthy control group. LIMITATIONS Analysis was based on self-report data, focusing on the difference with informants reports only. Conclusions about the direction of a possible bias on participants’ self-perception are limited. CONCLUSIONS Metacognitive deficits might play a key mediating role between the altered cognitive processes responsible for self-regulation and cognitive control and the daily-life consequences in BPD. BACKGROUND Military personnel and Veterans are at increased risk for suicide. Theoretical and conceptual arguments have suggested that elevated levels of acquired capability (AC) could be an explanatory factor accounting for this increased risk. However, empirical research utilizing the Acquired Capability for Suicide Scale (ACSS) in military populations has yielded mixed findings. METHODS To better ascertain what factors are associated with AC, and whether methodological limitations may be contributing to mixed findings, a systematic review was conducted. RESULTS A total of 31 articles utilized the ACSS to examine factors associated with AC, including combat history, in United States (U.S.) military personnel and Veterans. Nearly all studies (96.8%) were rated high risk of bias. Use of the ACSS varied, with seven different iterations utilized. Nearly all studies examined correlations between the ACSS and sample characteristics, mental health and clinical factors, Interpersonal Theory of Suicide constructs, and/or suicide-specific variables. Results of higher-level analyses, dominated by cross-sectional designs, often contradicted correlational findings, with inconsistent findings across studies. LIMITATIONS Included studies were non-representative of all U.S. military and Veteran populations and may only generalize to these populations. CONCLUSIONS Due to the high risk of bias, inconsistent use of the ACSS, lack of sample heterogeneity, and variability in factors examined, interpretation of current ACSS empirical data is cautioned. Suggestions for future research, contextualized by these limitations, are discussed. V.BACKGROUND Child sexual abuse (CSA) is a prevalent social problem associated with a plethora of difficulties in preschool children. Young victims are likely to show dissociation symptoms that may significantly impede their adaptation. Yet, mechanisms linking CSA with later dissociative symptoms remain unclear. The aim of the present study was to explore whether disorganized attachment and emotion dysregulation could act as mediators of the association between CSA and dissociation. METHODS A sample of 424 preschool children (274 CSA victims, 150 comparison group children; 3.5-6 years old) and their parents were recruited. Parents reported on children’s emotion dysregulation at initial assessment while attachment representations were assessed through children’s narratives using the Attachment Story Completion Task (Bretherton et al., 1990) coded with the Q-Sort (Miljkovitch et al., 2004). Parents reported on children’s dissociative symptoms one year later. RESULTS Mediation analysis showed that disorganized attachment and emotion dysregulation mediated the association between CSA and dissociation.