Cline

Understanding the most appropriate workflow for biochemical HLA-associated peptide enrichment prior to ligand sequencing is essential to achieve optimal sensitivity in immunopeptidomics workflows. We describe the use of different detergents for HLA solubilisation as well as complementary workflows to separate HLA-bound peptides from HLA protein…[Read more]

CONCLUSIONS Lebanon, historically and currently, experiences a high number of injuries from many different external causes. To date, efforts have focused on reporting the prevalence of injuries and making recommendations, rather than implementing and evaluating interventions and programs to inform policies. Future injury related work should…[Read more]

The ischemic and primary vascular injury of the brainstem (BS) can determine, among other serious conditions, the brain death (BD) of the individual. We present 2 cases of individuals with primary ischemic vascular disease of the BS who evolved to BD and were donors of solid organs and tissues. In both cases, the clinical examination was positive…[Read more]

Carotenoids are lipid-soluble yellow to orange pigments produced by plants, bacteria, and fungi. They are consumed by animals and metabolized to produce molecules essential for gene regulation, vision, and pigmentation. Cave animals represent an interesting opportunity to understand how carotenoid utilization evolves. Caves are devoid of light,…[Read more]