Frederiksen

9% to 88.0%, BNO increased from 4.9% to 6.2%, and BNGE decreased from 13.3% to 5.8%. Neuroimmunology/multiple sclerosis drugs represented >50% of the total payments despite being only 4.3% of claims.

Payments for neurologist-prescribed brand name, but not generic, drugs in Medicare Part D increased consistently and well above inflation…[Read more]

In general, FDE modeling approaches may be worth it in situations with large refined data sets and good numerical algorithms.To characterise the burden of work-related injuries in South Australia, workers’ compensation claim data were obtained from SafeWork South Australia between 2000 and 2014. Descriptive analyses were performed to investigate…[Read more]

Single-cell RNA sequencing is a powerful tool to study developmental biology but does not preserve spatial information about tissue morphology and cellular interactions. Here, we combine single-cell and spatial transcriptomics with algorithms for data integration to study the development of the chicken heart from the early to late four-chambered…[Read more]

Optimistic expectations also predicted less emotional distress before the event. There was no evidence that optimistic expectations related to longer-term greater distress when participants experienced an unexpected negative outcome; the valence of the outcome itself predicted distress. These results are consistent with the EMT-derived hypothesis…[Read more]