Sanders

Although bisphenol A (BPA) has been associated with impaired spermatogenesis, the mechanisms remain unclear. Tight junction occludin plays important roles in spermatogenesis. The objective of the present study was to explore the effects of BPA exposure in adolescent mice. Male mice were orally treated with low-dose (0.05 mg/kg/d), middle-dose (5.0…[Read more]

In multivariate analysis, age was an independent risk factor of MCI aggravating, while attention (MoCA) was independent protective factor for MCI progression.Conclusions Age and worsening attention but not depression in MCI patients were independently associated with the progression of dementia in a 6-year follow-up period.As a by-product during…[Read more]

The prevalence of transmitted drug resistance (TDR) was investigated among 178 patients with new diagnosis of HIV-1 infection (57% with B subtype) performed between 2017 and 2019. Overall, the global prevalence of TDR was 7.9% (NRTIs, 3.9%; NNRTIs, 3.4%; PIs, 2.8%, INSTIs, 0.9%). The most frequent mutations were T215S/I/D (3.4%) in the reverse…[Read more]

This article reviews endovascular management of chronic post-dissection aneurysms of the aortic arch. Therapeutic strategies intended for this complex aortic condition are evolving rapidly to allow the treatment of various hostile aortic anatomy and frail patients. Principles, technical considerations, devices and outcomes of each technique are…[Read more]

Further, to understand the mechanism underlying ovarian AA accumulation, the expression levels of SMP30/GNL and GULO genes were measured. Expression of both the genes was significantly suppressed, which suggested a lowered AA synthesis in the PMSG treated rat ovary. For further understanding, mRNA expression of AA transporters SVCT1 and SVCT2…[Read more]