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The purpose of this study was to analyze the traumatization degree of meta-epiphyseal cancellous of hip and knee joints in major orthopedic surgery that affects the incident of deep vein thrombosis (DVT) event through the dynamics expression of pro-thrombogenic biomarkers (Collagen I, Collagen IV, Tissue Factor, P-selectin) and anti-thrombogenic (Nitric Oxide).

In this cohort prospective study, there were sixty-nine (69) subjects that were divided into three (3) groups, with twenty-three (23) subjects that were treated with total arthroplasty (TA), twenty-two (22) subjects were treated with hemiarthroplasty (HA), twenty-four (24) subjects were treated with open reduction internal fixation (ORIF). Subjects from May 2010 to September 2011 who met the inclusion criteria were included in this study. All patients were treated without thromboprophylaxis. Blood samples were taken in three different periods, before surgery, 72h, and 144h after surgery, for examination of pro-thrombogenic biomarkers (Collagen I, Ctudied (Col IV, TF, and Ps) could not be proven. Future studies are needed to evaluate other biomarkers in the complex process of hemostasis to establish the diagnose of DVT.

This research confirms that trauma magnitude of the meta-epiphyseal cancellous of hip and knee joints in major orthopedic surgery influences the incidence of DVTs, through the elevation of Col I and NO. An estimated 72 h after surgery is a useful period to examine these biomarkers to help predict the diagnose of DVT. The involvement of the other biomarkers studied (Col IV, TF, and Ps) could not be proven. Future studies are needed to evaluate other biomarkers in the complex process of hemostasis to establish the diagnose of DVT.

Paradoxical emboli (PDE) represent less than 2% of all arterial emboli, that is why they are considered as a rare event. We notice that the upper limb ischemia is very exceptional as part of a paradoxical embolism. This case presentation can help in considering the diagnosis the PFO as one of the most important risk factors of paradoxical embolism.

Here, we present a rare case of a 69-year-old woman with paradoxical systemic arterial embolism, presented by an acute ischemia of the upper limb, secondary to deep venous thrombosis and pulmonary embolism in the presence of patent foramen ovale, treated with long-term anticoagulation with rivaroxiban 20 mg/day, because of the mutation of the Factor II whish indicate already the anticoagulation.

Echocardiographic techniques such as transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), or transcranial echocardiography (TCE) are the principal tools used to detect PFO. There are no clear consensus on the treatment of PDE. Presenting symptoms largely depend upon the location of the embolus, necessitating a different approach for each patient, but There is essentially three therapeutic options surgical embolectomy, thrombolysis, and anticoagulation.

PFO closure is, today, a standardized and safe intervention, but the indication stay individualized to each patient.

PFO closure is, today, a standardized and safe intervention, but the indication stay individualized to each patient.

The hemostatic agents have increased the bleeding complication in many surgeries. The SURGICEL is a preparation of oxidized cellulose regenerated from alpha-cellulose in an organic solvent, this product has the characteristic of resorbing without having a reaction of foreign body in 4-8 weeks.

We report the case of a patient operated on for a chondrosarcoma of the right temporomandibular joint with normal postoperative consequences, nevertheless after 3 months, the patient consulted again for the same symptomatology. To rule out tumor recurrence, magnetic resonance imaging has been requested; which showed a lesion well limited in T1 hypointense and heterogeneous in T2. During the surgical revision, we discover the presence of a reworked fibrous material, this material was the surgicel used for hemostatic purposes during the first surgery.

Hemostatic agents significantly reduced bleeding complications. But some authors are observed that some substances can persisted after 8 weeks of using, clinical manifestations depend of operative site. The diagnosis is suspected behind an imaging resonance aspect of a lesion well limited in T1 hypointense and heterogeneous in T2, but the discovery of a reworked fibrous materiel when the revision can confirm it.

the absence of degradation of the surgicel can clinically mimic a superinfection or even tumor recurrence; imaging guide the diagnosis but only the surgical revision can confirm it.

the absence of degradation of the surgicel can clinically mimic a superinfection or even tumor recurrence; imaging guide the diagnosis but only the surgical revision can confirm it.

Cleft lip with or without cleft palate is one of the most common birth defects and is certainly the most visible. Fistula rate after primary palatoplasty was ranging between 10 and 23% and could be detected in the first three weeks after surgery. The cleft width is the frequent factor which was assumed to correspond to fistula occurrence. This study aimed to find correlation between fistula occurrence with cleft width and palatum width ratio after primary palate repair.

A prospective cohort study was conducted on 16 subjects, which consisted of 10 males and 6 females. We measured width of cleft palate, width of rest palate and width of palate arch on three level measurements (posterior, junction and anterior). The surgery was performed using the two-flap and three layers suturing technique.

Sixteen patients were enrolled in this study during January and February 2008 . Ten patients were diagnosed with unilateral cleft palate while six patients had bilateral cleft palate. Mean of age was 22.31±5.86 month. Correlation analysis between fistula occurrence and cleft width, cleft width-remnant palate width ratio and cleft width-palate arch width ratio using logistic regression did not show statistical correlation, and the same result was found between fistula occurrence and hemoglobin level, white blood count, nutritional status, cleft type and caries dentis factors (

>0.05).

Width of the cleft is not a factor associated with fistula occurrence. Two-flap three layers technique could be considered as a simple technique and gives a low rate of fistula occurrence.

Width of the cleft is not a factor associated with fistula occurrence. Belumosudil Two-flap three layers technique could be considered as a simple technique and gives a low rate of fistula occurrence.