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The efficiency of dsRNA uptake mechanisms varies across species, and in some uptake is negligible, rendering them effectively resistant to this new generation of control technologies. If RNAi-based methods of control are to be used widely, it is critically important to understand the mechanisms underpinning dsRNA uptake. Understanding dsRNA uptake…[Read more]

In this chapter, we discuss immune modulatory functions of TAM receptors in the tumor microenvironment as well role of differentially expressed TAM receptors and their interactions with immune and tumor cells. Finally, we describe current strategies being utilized for targeting TAMs in several cancers and their implications in immunotherapy.The…[Read more]

03), greater E/E’ ratio (p = 0.005) and longer MPI (p  less then  0.001). Gestational age  less then  32 weeks is independently associated with current asthma in adolescence. Children 13-14 years old born very preterm required more respiratory admissions and had poorer diastolic and global function of both ventricles. IUGR is a risk factor for…[Read more]

The authors sought to examine relationships between CT metrics derived via an automated method and clinical parameters of extraocular muscle changes in thyroid eye disease (TED).

CT images of 204 orbits in the setting of TED were analyzed with an automated segmentation tool developed at the institution. Labels were applied to orbital…[Read more]

The Indian government announced a nationwide lockdown as a preventive measure to control the prevailing COVID-19 pandemic. Sumatriptan This survey was developed and conducted to assess the impact of lockdown on Indian optometry practice.

A survey questionnaire was designed and circulated across the optometrists practicing in India through…[Read more]

To describe a single-center 15-year experience of active surveillance (AS) for prostate cancer (PCa).

We retrospectively reviewed patients who underwent AS between 2003 and 2018. One hundred fifty-three patients were selected according to the following criteria (1) biopsy Gleason pattern ≤3+4 with (2) ≤two positive core(s) and (3) ≤50…[Read more]

5% (0.7%-16%) and 2.3% (0.6%-6%), p=0.37) was observed indicating that microaspirations were not significantly decreased after optimized versus routine oral care.

Suctioning by the subglottic port of endotracheal tubes may not decrease the risk of microaspiration during oral care of ventilated patients.

Suctioning by the subglottic port…[Read more]

Rates of sexual victimization have remained steady over several decades, and preventative interventions to reduce men’s sexually aggressive behavior have been largely ineffective. As such, research has endeavored to find novel approaches to identify women at increased risk for sexual victimization. Sexual assault scripts, or “cognitive models”…[Read more]