Moos

The purpose of this review is to enhance our understanding of the interactions of prebiotics and probiotics, which sheds new light on the future use of oligosaccharides and bifidobacteria for nutritional intervention or clinical application.The current work focuses on a cheap and simple preparation of highly conducting chitosan/hydroxyl…[Read more]

This study could provide the theoretical basis for the development of efficient azoles inhibitors and may lead a better insight into structure-function relationships of CYP51.Fluorescently labeled proteins can improve the detection sensitivity and have been widely used in a variety of biological measurements. In single-molecule assays,…[Read more]

Multifactorial haemostasis disorders are typical of patients with end-stage renal disease (ESRD) on chronic haemodialysis (HD). Thromboelastometry and impedance aggregometry allow for a comprehensive assessment of clot formation, lysis, and platelet (PLT) function. This study aims to determine the haemostatic profile in a group of patients with…[Read more]

The purpose of the study was to evaluate the efficacy of vacuum-gradient therapy in reducing orthodontic treatment time.

The study comprised 57 patients aged from 25 to 35 years (mean age 28.8±4.6 years) with teeth crowding divided into two groups. In group 1 (

=29) orthodontic correction was combined with vacuum-gradient therapy by means…[Read more]

The purpose of the study was to evaluate the efficacy of vacuum-gradient therapy in reducing orthodontic treatment time.

The study comprised 57 patients aged from 25 to 35 years (mean age 28.8±4.6 years) with teeth crowding divided into two groups. In group 1 (

=29) orthodontic correction was combined with vacuum-gradient therapy by means…[Read more]

Epilepsy is a neurological disease recognized as the consequence of excessive neuronal excitability. Endocannabinoid system, the critical regulator of synaptic inhibition in brain, was supposed to be closely involved in epilepsy. Cannabinoid receptors mostly locate on presynaptic terminals of both excitatory and inhibitory neurons, but with…[Read more]

chondrial permeability transition pore (mPTP) opening were recovered after TM treatment. It also down-regulated cytochrome c and apoptosis inducing factor contents after myocardial I/R injury. In vitro study showed that TM treatment reduced intracellular ROS content and recovered ΔΨ

in NRVMs after H/R injury. We also observed that TM could r…[Read more]

Time-Resolved Fluorescence Resonance Energy Transfer revealed that MMIs are weak ligands of human PXR. Collectively, we show that MMIs are ligands and partial agonists of human PXR, which induce PXR-regulated genes in human intestinal cells. As a consequence of the detoxification process, drugs and drug related metabolites can accumulate in the…[Read more]

The mean lethal concentration (LC50) was determined by the probit method. Subacute toxicity data indicated that there was no mortality or structural alterations of the liver and kidneys in the lot of treated animals. However, significant alterations in certain hematological and biochemical parameters (hematocrit, ASAT, and uremia) were noted.…[Read more]