Russo

Oxytocin (OT) has been implicated in various aspects of social behaviors. During the past decades there has been a surge of interest in the therapeutic potential of OT in psychiatric disorders, especially those characterized by social deficits, which the available therapeutic agents, cannot fully target. This systematic review and meta-analysis…[Read more]

There are many studies that model the within-host population dynamics of Human Immunodeficiency Virus Type 1 (HIV-1) infection. However, the within-infected-cell replication of HIV-1 remains to be not comprehensively addressed. There exist rather few quantitative models describing the regulation of the HIV-1 life cycle at the intracellular level.…[Read more]

Our results indicate that the relative population as well as the structure of the dimer state is modulated by membrane composition. We have correlated these differences to local perturbations of the membrane around the receptor. EZM0414 chemical structure Our work is an important step in characterizing ErbB dimers in healthy and diseased states…[Read more]

Results Most cats in remission continued to display impaired glucose tolerance. Concentrations of 16 identified metabolites differed (P ≤ 0.05) between remission and control cats 10 amino acids and stearic acid (all lower in remission cats), and glucose, glycine, xylitol, urea and carnitine (all higher in remission cats). Moderately close c…[Read more]

Background/Aims Constipation shows both, a high prevalence and a significant impact. However, it is often perceived as minor and treatment choices are limited. The neuromodulation approach is a valuable option to be considered. This study assesses the use of non-invasive sacral nerve stimulation to reduce constipation in children. Methods Between…[Read more]

The COVID-19 pandemic has foisted unprecedented changes upon graduate medical education ranging from adjustments to patient care practices to adaptive modifications to educational activities. To comply with social distancing guidelines, in-person conferences and didactics have been suspended in most, if not all residency programs throughout the…[Read more]