Neal

ay provide a molecular explanation for a severe or prolonged progression of disease in select COVID-19 patients.COVID-19, caused by SARS-CoV-2 involves multiple organs including cardiovascular, pulmonary and central nervous system. read more Understanding how SARS-CoV-2 infection afflicts diverse organ systems remains challenging 1,2 .…[Read more]

Under poikilocapnic conditions neither facial cooling nor CPT evoked a change in middle cerebral artery blood flow velocity (MCA Vmean ; transcranial Doppler) (P > 0.05 vs. baseline). Under isocapnic conditions, facial cooling did not change MCA Vmean (P > 0.05), whereas CPT increased MCA Vmean by 13% (P  0.05). Finally, MCA Vmean and ICAQ were…[Read more]

Finally, we also discuss potential challenges in future studies of SA signaling pathway.Lymphopenia is commonly observed in SARS and COVID-19 patients although the lymphocyte count is not always below 0.8 × 109 /L in all the patients. It is suggested that lymphopenia serves as a useful predictor for prognosis in the patients. It is also…[Read more]

859) with sensitivity of 88.9% and specificity of 77.3%. The complementary whole-brain tract-based spatial statistics (TBSS) showed that widespread increases of FA were found in the SO group compared with HCs, but were not associated with the onset of BD. Our data provide evidence supporting the causal relationship between the white matter…[Read more]

The bacteria of the genus Streptomyces and Basidiomycete fungi harbor many biosynthetic gene clusters (BGCs) that are at the origin of many bioactive molecules with medical or industrial interests. Nevertheless, most BGCs do not express in standard lab growth conditions, preventing the full metabolic potential of these organisms from being…[Read more]

In this study we investigated the effect of predictability on dual-task performance in two experiments. In the first experiment 33 participants separately practiced a continuous tracking task and an auditory reaction time task. Both tasks had a repeating element that made them predictable; in the tracking task this was a repeating segment, and in…[Read more]

Madelung disease is a rare lipid metabolic disorder, and most cases are sporadically reported. There are currently no systematic reviews summarizing the epidemiological and clinical characteristics of this disease. The purpose of the current article is to extract and analyze the existing evidence concerning Madelung disease derived from case…[Read more]