Kramer

This is the first study where the AGT rs1926723 variant, TP53 rs4968187, and MGMT rs7896488 were found to be associated with the risk of developing an astrocytoma.The original version of the article unfortunately contained a typo in co-author name. The author name should be Francesco Paolo Fanizzi instead it was published incorrectly as Franco…[Read more]

However, significantly poorer progression-free survival (PFS) (p = 0.004) was observed in Group 1 (median 12 months) compared with Group 2 (median not reached). Multivariate analyses identified HSCT after KRd as potential risk factors associated with PFS. Also, in Group 1, bortezomib refractoriness was associated with significantly shorter PFS…[Read more]

Iron tailings are fine, stable and complex materials, which are mainly composed of minerals and metal oxides. Residual silicon in iron tailings can be used to prepare mesoporous silica materials applied to energy storage, environmental protection and other fields. This paper reported a novel synthesis strategy from iron tailings to high-surface…[Read more]

A very large number of computational methods to predict the change in thermodynamic stability of proteins due to mutations have been developed during the last 30 years, and many different web servers are currently available. Nevertheless, most of them suffer from severe drawbacks that decrease their general reliability and, consequently, their…[Read more]

In addition, an intrinsic ChrB protein fluorescence assay suggested that pH and salinity may influence the Cr(VI) adsorption capacity of ChrB-expressing E. coli cells by modulating the ChrB protein conformation. Although the characteristics of ChrB may not be universal for all metal-binding proteins, our study provides new insights into different…[Read more]

Hidradenitis suppurativa (HS) is a potentially debilitating dermatological disease that negatively impacts patients’ quality of life. Severe cases can be further complicated by persistent granulation tissue at the ostia of sinus tracts, which may prove recalcitrant to standard interventions. Herein we report such a case in which a patient…[Read more]