Wiese

Plasmodial transketolase (PTKT) enzyme is one of the novel pharmacological targets being explored as potential anti-malarial drug target due to its functional role and low sequence identity to the human enzyme. Despite this, features contributing to such have not been exploited for anti-malarial drug design. Additionally, there are no…[Read more]

In summary, we have identified a novel role for Nod2 and demonstrate that Nod2 protects from HFD-dependent liver malignancy and this protection is accompanied by decreased cell proliferation, inflammation, steroid biosynthesis, neutrophils and macrophages infiltration, and STAT3 and MAPK signaling in the liver.Muscular dystrophies (MDs) are…[Read more]

Diabetes has been associated with poor outcomes following burn injury. There is limited data related to prediabetes in burn injury, and no studies to date have compared clinical outcomes inpatients without diabetes, with prediabetes, and with diabetes. Therefore, this study aimed to compare clinical outcomes after burn injury across the continuum…[Read more]

High intensity focused ultrasound (HIFU) is a widely used technique capable of providing non-invasive heating and ablation for a wide range of applications. However, the major challenges lie on the determination of the position and the amount of heat deposition over a target area. In order to assure that the thermal area is confined to tumor…[Read more]