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Pituitary adenylate cyclase activating polypeptide (PACAP) is involved in development and reproduction. We previously described elevated PACAP levels in the milk compared to the plasma, and the presence of its specific PAC1 receptor in the mammary gland. This study aimed to determine PACAP and vasoactive intestinal peptide (VIP) levels in female…[Read more]

SWI/SNF (BAF) complexes are a diverse family of ATP-dependent chromatin remodelers produced by combinatorial assembly that are mutated in and thought to contribute to 20% of human cancers and a large number of neurologic diseases. The gene-activating functions of BAF complexes are essential for viability of many cell types, limiting the…[Read more]

04 ± 1.0 (p-value 0.046). Women taking estrogen had lower mean BMD at the lumbar spine 0.952 ± 0.086 g/cm2, compared to women not taking estrogen 1.023 ± 0.105 g/cm2 (p-value 0.038). Similar trends were seen at the total hip and femoral neck. Conclusion Low-dose estrogen supplementation in premenopausal women with CF was associated with lower BM…[Read more]

In this work, nitrogen-doped carbon nanoshell structure with the encased Fe0/Fe3C nanoparticles (Fe@NC) was synthesized with a solvent-free method via direct carbonizing the ground mixture of dicyandiamide and ferric chloride hexahydrate. The morphology, structure, and surface properties of as-synthesized Fe@NC were characterized systematically,…[Read more]

K-Means is one of the most popular clustering algorithms that partitions observations into nonoverlapping subgroups based on a predefined similarity metric. Its drawbacks include a sensitivity to noisy features and a dependency of its resulting clusters upon the initial selection of cluster centroids resulting in the algorithm converging to local…[Read more]

Results Among all chitosan oligosaccharides, the COS > degrees of polymerization (DP) 4 showed anti-inflammatory activities (the activity order was chitopentaose 4). The levels of ROS/RNS had a strong relationship with cardiac parameters. Conclusions Chitoheptaose plays a myriad of cardioprotective roles in the myocarditis model via its antioxi…[Read more]