Martinsen

THIM is a new wearable device worn on the finger that can passively monitor sleep and wakefulness overnight using actigraphy. This article showcases the development of the THIM sleep tracking algorithm (Study 1) and the testing of its accuracy against polysomnography (PSG) with an independent sample of good and poor sleepers (Study 2). The…[Read more]

High levels of depressive symptoms were associated with a 22-fold increase (95% confidence interval, 8.9 to 53.5) in the odds of improper use of inhaler devices after adjustment for potential confounders.

As a result, the presence of depression symptoms may increase the improper use of inhaler devices. Further research is needed to…[Read more]

Schwannoma, also known as neurilemmoma, is a tumor of the nerve sheath, which most often occurs in the peripheral nerves of the extremities. Schwannoma can be accompanied by symptoms such as pain, paresthesia, and Tinel sign; however, patients can also be asymptomatic. Here, we present the case of a 17-year-old woman who presented with a slowly…[Read more]

To review the effectiveness of health education interventions adapted for culturally and linguistically diverse (CALD) populations with a chronic illness.

A systematic review and meta-analysis were conducted. Eligible studies were identified across six databases. Data were extracted and intervention effect was summarized using standardized…[Read more]

In 18 genes, we identified 36 compound heterozygous variants, whereas in the other 18 genes we identified 18 de novo variants. Twelve of 36 candidate risk genes are known to play a role in transmembrane transport, adaptive and innate immunity, and epithelial barrier function.

The 36 candidate genes for early-onset PSC need further…[Read more]

In addition, the phosphorylated protein expression levels of mitogen-activated protein kinase kinase 5 (ASK1) and JNK increased following wogonoside treatment, and the protein expression levels of tumor necrosis factor receptor-associated factor 2 (TRAF2) and serine/threonine-protein kinase/endoribonuclease IRE1 (IRE1α) were also increased…[Read more]

A well-controlled innate immune response is characterized by a rapid yet self-limiting inflammatory response. Although much is known about the range of inflammatory stimuli capable of triggering an innate immune response, the mechanisms which govern the degree of inflammation induced by inflammatory insults and the mechanisms in place to reset or…[Read more]

007 to 0.027) units, 2.6 (-1.3 to 6.5) L·min

and 1.4 (-0.8 to 3.5) beats·min

, respectively. Agreement (95% limits of agreement) for

‘

peak, RER and

‘

was 0.2 (±3.7) mL·kg

·min

, 0.01 (±0.10) units and 2.6 (±24.0) L·min

, respectively. No systematic or proportional bias was found except for the completed dista…[Read more]