Walls

BACKGROUND Randomized-controlled trials (RCTs) reported a finding on the safety and efficacy of percutaneous patent foramen ovale (PFO) closure to prevent stroke recurrence. It showed that the Amplatzer (AMP) device appears to be superior to medical therapy (MT) in preventing strokes and episodes of atrial fibrillation (AF), than other devices. We…[Read more]

Background Migrants from certain regions are at increased risk of key infectious diseases (including HIV, tuberculosis (TB), hepatitis B and hepatitis C). Although guidelines increasingly recommend integrated screening for multiple infections to reduce morbidity little is known about what migrants and healthcare professionals think about this…[Read more]

Cellular stress induced by the abnormal accumulation of unfolded or misfolded proteins at the endoplasmic reticulum (ER) is emerging as a possible driver of human diseases, including cancer, diabetes, obesity and neurodegeneration. ER proteostasis surveillance is mediated by the unfolded protein response (UPR), a signal transduction pathway that…[Read more]

SIGNIFICANCE STATEMENT The cerebellum interacts with several distinct large-scale brain networks for cognitive function, but the factors governing selectivity of such interactions for particular functions are not fully understood. We tested the hypothesis that cerebellar contributions to cognition are guided by neural oscillations with…[Read more]

Quarantine is a major stressful event disrupting social zeitgebers for people who have had contact with infected individuals, especially for vulnerable individuals with a hypersensitive reward system. see more Stress could act as a trigger in the onset of manic episode, so psychological support should be more targeted at the vulnerable individuals…[Read more]

The proton precession magnetometer (PPM) is a commonly used device to measure the varying magnetic field. Since the frequency of the PPM sensing free induction decay (FID) signal is proportional to the magnetic field, the signal-to-noise ratio (SNR) is always a critical issue that influences the measurement accuracy severely due to the external…[Read more]

Among the 28 admitted patients, 24 were discharged as of February 26, 2020, with an average hospital stay of 14.96 (±4.27) days, which was not significantly associated with the interval between the onset of symptoms and admission. Conclusions In the absence of specific antiviral drugs or a vaccine, quarantine or isolation is the most effective…[Read more]

Study design In this study, we decided to change the activity of periaqueductal gray (PAG)’s metabotropic glutamate receptors subtype 8 (mGluR8) by means of its specific agonist, (S)-3,4-dicarboxyphenylglycine (DCPG), and by knock downing it with mGluR8 siRNA. We then evaluated the changes in animal pain threshold levels in the face of painful…[Read more]