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24 (95% CI = 1.21-1.28, P  less then  .001). In subgroup analyses performed according to age and sex, all crude and adjusted hazard ratios of herpes zoster were higher in the peptic ulcer disease group than in the control group (each P  less then  .05). In another subgroup analysis according to follow-up periods, the crude and adjusted hazard…[Read more]

Additionally, ceramide metabolism, tryptophan degradation, and reductions in several metabolic reactions involving nicotinamide adenine nucleotide (NAD) at inclusion were significantly associated with respiratory severity and correlated with inflammation. In summary, assessment of the metabolomic profile of COVID-19 patients could assist in…[Read more]

The coronavirus disease 2019 (COVID-19), caused by the virus SARS-CoV-2, is an acute respiratory disease that has been classified as a pandemic by the World Health Organization (WHO). The sudden spike in the number of infections and high mortality rates have put immense pressure on the public healthcare systems. Hence, it is crucial to identify…[Read more]

Clinical depression affects 17.3 million adults in the U.S. However, 37% of these adults receive no treatment, and many symptoms remain unmanaged. Mobile health apps may complement in-person treatment and address barriers to treatment, yet their quality has not been systematically appraised. We conducted a systematic review of apps for depression…[Read more]

To our knowledge, this is the first study of using dissolving microneedles and exploring their utilization with imiquimod for the treatment of warts. First, we added fluorescent dye and trypan blue into the microneedles to evaluate the status of drugs in the microneedles and the degradation property of microneedles made of gelatin, respectively.…[Read more]

Among them, the 15 μl L-1 H2S treatment had the best effect on fresh-cut Chinese water chestnuts.Vitamin D is a pro-hormone, essential for musculo-skeletal health, normal immune system, and numerous other body functions. Vitamin D deficiency is considered as a risk factor in many conditions, and there is growing evidence of its potential role in…[Read more]

This study highlights sciadopitysin as a promising candidate for antioxidant therapy and designing natural drugs against AGE-induced neurodegenerative disorders.To extend marketing exclusivity, a drug manufacture is required by the Food and Drug Administration to conduct an interpretable study of approved drugs that may benefit pediatric patients.…[Read more]

g the prevalence of hypertension in obese children and adolescents.

To investigate the distribution, characteristics, and association with subarachnoid hemorrhage (SAH) of aneurysms identified in Turkish adult patients with computed tomography angiography (CTA) performed with suspicion of intracranial aneurysms and/or SAH.

A total of…[Read more]