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McGuire posted an update 7 months, 1 week ago
007).
This is the first case-control study assessing the outcomes of TP in women with RD. An increased risk of preterm delivery, emergency cesarean section and admission to NICU as compared to both SP in RD and TP in the GOP was observed. Multidisciplinary management is warranted to minimize these risks.
This is the first case-control study assessing the outcomes of TP in women with RD. An increased risk of preterm delivery, emergency cesarean section and admission to NICU as compared to both SP in RD and TP in the GOP was observed. Multidisciplinary management is warranted to minimize these risks.
To evaluate the influence of ABO and Rh blood groups on morbidity among SARS-CoV-2 infected pregnancies.
Prospective observational study.
78 centers of the Spanish Obstetric Emergency Group.
Pregnant women with SARS-CoV-2 tested with polymerase-chain-reaction between 26-February and 5-November 2020. A cohort of 1278 SARS-CoV-2(+) pregnant women was analyzed and a concurrent comparison group of 1453 SARS-COV-2(-) patients was established.
Data were collected from medical charts. SARS-COV-2(+) was compared with SARS-COV-2(-) for differences in distribution of blood groups. We performed multivariate analysis, controlling for maternal age and ethnicity, to evaluate association of ABO and Rh blood groups with maternal and perinatal outcomes in SARS-CoV-2(+) patients with adjusted odds ratios (aOR) and 95% confidence intervals (CI).
Medical morbidity Symptomatic COVID-19 and medical complications. Obstetric outcomes caesarean delivery, preterm deliveries, preterm premature rupture of membranes (PPROM), hemorrhagic events, pre-eclampsia, maternal and neonatal mortality, stillbirth.
Differences were noted between blood types and Rh for age and ethnicity comparing SARS-CoV-2(+) and SARS-CoV-2(-) groups (p<0.05). Among the SARS-CoV-2(+) cohort, the odds of symptomatic COVID-19 and obstetric hemorrhagic event were higher in Rh+ vs Rh- mothers (aOR 1.48, 95% CI 1.02-2.14, p=0.037, and aOR 8.72, 95% CI 1.20-63.57, p=0.033, respectively), and PPROM were higher among blood type A vs non-A mothers (aOR 2.06, 95% CI 1.01-4.18, p=0.046).
In SARS-CoV-2(+) pregnant women, Rh- status was associated with a lower risk of symptomatic COVID-19, while Rh+ and blood group A were associated with obstetric hemorrhage and PPROM, respectively.
In SARS-CoV-2(+) pregnant women, Rh- status was associated with a lower risk of symptomatic COVID-19, while Rh+ and blood group A were associated with obstetric hemorrhage and PPROM, respectively.
To demonstrate the experience of laparoscopic radical hysterectomy for cervical cancer without the use of a uterine manipulator and investigate the feasibility and treatment effectiveness of this surgical approach.
The laparoscopic radical hysterectomy for cervical cancer by pulling the round ligament without a uterine manipulator prevented the oppression of the uterine manipulator on the tumour. Vaginal ligation was performed below the lesion of cervical cancer, and the vagina was cut off below the ligation line. Consequently, the exposure of cancer tissues in the abdominal cavity was prevented, enabling a tumour-free operation. We reviewed the medical records of the 22 patients with stage IB1-IIA2 cervical squamous cell carcinoma who were treated at our hospital between May 2019 and February 2020. All the patients underwent the laparoscopic radical hysterectomy for cervical cancer by pulling the round ligament. All the patients were informed about the different therapeutic schemes and surgical approachepears to be safe and feasible for patients with cervical cancer. A larger sample size and longer follow-up period are required to confirm whether this surgical approach can actually and effectively improve the prognosis.
This surgical approach appears to be safe and feasible for patients with cervical cancer. A larger sample size and longer follow-up period are required to confirm whether this surgical approach can actually and effectively improve the prognosis.
The aim of this study was to measure the impact of innovative pelvic floor muscle training (iPFMT) on Quality-Adjusted Life Years (QALYs) in women with stress urinary incontinence (SUI) treated by duloxetine.
This analysis is part of the DULOXING study conducted between February 2019 and 2020. The control group received oral duloxetine treatment (40mg BID), and the experimental group received oral duloxetine treatment (40mg BID) and iPFMT with lumbopelvic stabilization. SUI was analysed at baseline and in the final period according to the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF). selleck products The QALYs gained were calculated by multiplying life expectancy (LE) by a weighting factor (QALYs=LE * WF).
The study included 158 women, of whom 129 were fully analysed (81.6%). The mean life expectancy was 26.3±11.8years for the control group and 29.0±11.7years for the experimental group. The mean baseline ICIQ-UI SF scores were 15.2±1.7 vs 15.1±1.5, and the final ICIQ-UI SF scores were 9.8±4.2 vs 8.3±3.8, in the control vs the experimental group, respectively (p<0.05). The mean baseline WF was 0.27±0.08 vs 0.28±0.07, and the final WF was 0.53±0.20 vs 0.60±0.18, in the control vs the experimental group, respectively (p<0.05). Before treatment, the number of QALYs during life expectancy in the control vs the experimental group was 7.53±4.24 vs 8.30±4.01. The number of QALYs during life expectancy in control vs the experimental group increased following treatment 15.03±7.63 vs 17.90±7.86 (p<0.05).
Combination treatment with duloxetine and iPFMT statistically significantly increased the number of QALYs and reduced the degree of urinary incontinence in women with stress urinary incontinence.
Combination treatment with duloxetine and iPFMT statistically significantly increased the number of QALYs and reduced the degree of urinary incontinence in women with stress urinary incontinence.
The optimal timing of umbilical cord clamping in preterm infants has been contested foryears.Previously, itwascommon practice to clamp the cordimmediatelyafterbirth.There is now high-quality evidence that delayed cord clamping (DCC) (>60seconds)reduces mortality in preterm infants byallowingplacental transfusion.However, it is unclear how well DCChas been implemented into practice. This study aimstoassess current practice of timing of cord clamping for both stable and unstable preterm infants in LMICs, where rates of preterm birth and neonatal mortality are high and where there is the potential to see the greatest benefit from implementation of DCC.
Anonline survey was created and, following user-testing, circulated to maternity workers in LMICs via The International Federation of Gynaecology and Obstetrics (FIGO), social media and other existing collaborators. Analyses were conducted using SPSS.
70 responses were received across 10 LMICs. 42/70 (60%) participants reported practising DCC for stable preterm infants, compared to only 4/70 (6%) for unstable infants.