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These findings have implications for the emergence of antimicrobial resistance in gonococci and how this is associated with lineages, some of which are more predisposed to developing antimicrobial resistance than others. © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.BACKGROUND Low serum…[Read more]

Practitioners should be aware of the safe injection techniques, potential complications, and management of these complications for a good clinical practice. © 2020 Wiley Periodicals, Inc.BACKGROUND Augmented reality (AR) is a simulation of a three-dimensional environment created using hardware and software that provides the user with realistic…[Read more]

Ovarian cancer (OC) is the fifth most frequent cause of cancer-associated mortality worldwide, and is accompanied by asymptomatic progression. Sirtuins (SIRTs) are a family of nicotinamide adenine dinucleotide-dependent protein deacetylases, comprising seven members (SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6 and SIRT7). Accumulating evidence has…[Read more]

6 ± 33.4, p = 0.025). The mean MSA survival time was 5.4 [95% confidence interval (CI) 4.8-6.3] years. Cox regression analysis showed that survival from baseline was correlated only with BCI [hazard ratio (HR) 0.983, 95% CI 0.969-0.997, p = 0.020]. Overall survival was correlated with BCI (HR 0.982, 95% CI 0.966-0.999, p = 0.039) and the presence…[Read more]

OBJECTIVE To determine whether infants with severe persistent sleep problems are at increased risk of (1) meeting diagnostic criteria for a psychiatric disorder (age 10 years), and (2) having elevated symptoms of mental health difficulties (ages 4 and 10 years), in comparison with infants with settled sleep. DESIGN AND SETTING Prospective…[Read more]

Introduction Yellow oleander (Thevetia peruviana), which belongs to the Apocyanaceae family, is a common shrub seen throughout the tropics. All parts of the plant contain high concentrations of cardiac glycosides which are toxic to cardiac muscle and the autonomic nervous system. Here, we describe the clinical profile of patients with oleander…[Read more]

Moreover, quantification allowed identification of hyper-metabolic areas that are associated with frequently spiking cortex, rarely acknowledged in clinical readings. Overall, besides providing some confirmatory information to visual readings, quantitative PET imaging demonstrated only a moderate impact on clinical management of patients with…[Read more]

CONCLUSIONS In considering the many factors involved in thirst arousal and inhibition, similar questions need to be considered for the correct assessment of this ingestive behavior.This study aims to develop the Attitudes and Beliefs Scale about Sexuality during Pregnancy (ABSSP) and to test its validity and reliability. The study utilized a…[Read more]

Assessing ecosystem vulnerability to climate change is critical for sustainable and adaptive ecosystem management. Alpine grasslands on the Qinghai-Tibetan Plateau are considered to be vulnerable to climate change, yet the ecosystem tends to maintain stability by increasing resilience and decreasing sensitivity. To date, the spatial pattern of…[Read more]

Minesapride (drug code DSP-6952) is a potential gastrointestinal prokinetic agent with high selectivity for 5-hydroxytryptamine 4 (5-HT4 ) receptor that acts as a partial agonist. Although 5-HT4 receptor agonists are expected to show efficacy in patients with irritable bowel syndrome with constipation, only tegaserod is available for female…[Read more]

These results highlight the negative association between neonatal seizures and functional development.We report a preregistered study that was designed to answer three questions about using transparent defaults to increase participation in a hypothetical learning health care system. Do default options influence consent to participate in learning…[Read more]